California - Significance region: Local
| San Diego Rowing Club |
| San Diego Trust and Savings Bank Building |
| San Diego Veterans' War Memorial Building-Balboa Park |
| San Dimas Hotel |
| San Fernando Building, The |
| San Francisco and North Pacific Railroad Station House-Depot |
| San Francisco Art Institute |
| San Francisco Central YMCA |
| San Francisco Fire Department Engine Co. Number 2 |
| San Francisco Juvenile Court and Detention Home |
| San Francisco Public Library North Beach Branch |
| San Gabriel Mission |
| San Gabriel Mission Playhouse |
| San Gregorio House |
| San Joaquin Light & Power Corporation Building |
| San Jose Central Fire Station |
| San Jose Downtown Historic District |
| San Juan Bautista Third Street Historic District |
| San Luis Obispo Carnegie Library |
| San Mateo County Courthouse |
| San Pedro Municipal Ferry Building |
| San Rafael Improvement Club |
| Santa Ana City Hall |
| Santa Ana Fire Station Headquarters No. 1 |
| Santa Barbara Club |
| Santa Barbara County Courthouse |
| Santa Barbara Veterans Memorial Building |
| Santa Clara Verein |
| Santa Cruz Downtown Historic District |
| Santa Fe Depot |
| Santa Fe Federal Savings and Loan Association |
| Santa Fe Freight Depot |
| Santa Fe Hotel |
| Santa Fe Passenger and Freight Depot |
| Santa Fe Railway Passenger and Freight Depot |
| Santa Monica Civic Auditorium |
| Santiago Orange Growers Association Packing House |
| San Timoteo Canyon Schoolhouse |
| Santora Building |
| Sara-Thel Court |
| Saratoga Foothill Club |
| Saratoga Village Library |
| Sargent, B. V., House |
| Saticoy Southern Pacific Railroad Depot |
| Sausalito Woman's Club |
| Sawyers Bar Catholic Church |
| Scarlett Ranch |
| Schaffer, J.W. House |
| Schindler, R. M., House |
| Schoenstein and Company Pipe Organ Factory |
| Schorlig House |
| Schramsberg Vineyard |
| Schreiber, Brock, Boathouse and Beach |
| Scott, Hiram D., House |
| Scott, Irving Murray, School |
| Scripps College for Women |
| Scripps Hall |
| Scully Ranch |
| Seabiscuit's Stud Barn |
| Seal Beach City Hall |
| Sebastopol Depot of the Petaluma and Santa Rosa Railway |
| Second and Howard Streets District |
| Second Baptist Church |
| Second Church of Christ Scientist |
| Second Church of Christ, Scientist |
| Security Bank and Trust Company Building |
| Security-First National Bank of Los Angeles |
| Security Trust and Savings |
| Security Trust and Savings Building |
| Semorile Building |
| Senior Hall |
| Senior Officers Quarters Historic District, Yerba Buena Island |
| Serrano, Jose, Adobe |
| Sexton, Joseph and Lucy Foster, House |
| Shadelands Ranch House |
| Shady Point |
| Shannon-Williamson Ranch |
| Shasta Inn and Weed Lumber Company Boarding House |
| Shaw, Isaac E., Building |
| Shell Gas Station |
| Shiloh Baptist Church |
| Shorty Lovelace Historic District |
| Shoup, Paul, House |
| Sieroty House |
| Sierra City School |
| Sierra Railway Locomotive No. 3 |
| Sierraville School |
| Silberstein Park Building |
| SILVERGATE (FERRY) |
| Simi Adobe-Strathearn House |
| Simmons, William Adam, House |
| Simon's, M. H., Undertaking Chapel |
| Simpson-Vance House |
| Sinatra, Frank, House |
| Singer Building |
| Sinton House |
| Site Number 4 Mnt 85 |
| Six Sisters-Lawn Way Historic District |
| Skidoo |
| Slocum House |
Data from United States Park Service and Wikidata
