California - Significance region: Local
| Smiley Park Historic District |
| Smith and Clark Brothers Ranch and Grounds |
| Smith, Ernest W., House |
| Smith Estate |
| Smith, Maurice, and Dinah Shore House |
| Smith-Tuthill Funeral Parlors |
| Smith, Williams, House |
| SMUD Headquarters Building |
| Snow Creek Ski Hut |
| Snow Flat Snow Survey Shelter |
| Soda Springs Cabin |
| Soda Springs Historic District |
| Sonoma Depot |
| Sonoma Grammar School |
| Sonoma Valley Woman's Club |
| Sonora Youth Center |
| South Berkeley Community Church |
| South Bonnie Brae Tract Historic District |
| Southern California Sanitarium Historic District |
| Southern Counties Gas Co. |
| Southern Hotel |
| Southern Pacific 16th Street Station and 16th Street Tower |
| Southern Pacific Depot |
| Southern Pacific Depot |
| Southern Pacific Passenger Depot |
| Southern Pacific Railroad Bayshore Roundhouse |
| Southern Pacific Railroad Company's Sacramento Depot |
| Southern Pacific Railroad Depot, Whittier |
| Southern Pacific Railroad Section Superintendent House |
| Southern Pacific Railroad Station |
| Southern Pacific Train Depot |
| South Marengo Historic District |
| South of Campus Neighborhood |
| South Pasadena Historic District |
| South San Francisco Hillside Sign |
| South San Francisco Opera House |
| South Serrano Avenue Historic District |
| Sovereign Hotel |
| Sowden, John, House |
| Special Internal Revenue Bonded Warehouse, First District, No. 13 |
| Spencer, John, House |
| Sperry Office Building |
| Sperry Union Flour Mill |
| Spoke Wheel Rock Alignment |
| Spotswood House |
| Spreckels Theatre Building |
| Spurgeon Block |
| Squatter's Cabin |
| Squire, John Adam, House |
| Stadtmuller House |
| Stage Stop |
| Standard Oil Building |
| Standish Hall |
| St. Andrews Bungalow Court |
| St. Andrews Square Historic District |
| Stanislaus Branch, California Forest and Range Experiment Station |
| Stansbury House |
| Stanton, Phillip Ackley, House |
| State Theatre |
| State Theatre |
| Steamship TENNESSEE Remains |
| Steedman Estate |
| Stevens House |
| Stevenson, Robert Louis, Branch |
| Stevens, Sherman, House |
| Stevens Trail |
| St. Francis by-the-Sea American Catholic Church |
| St. Francis Mission Church |
| St. Francis Wood Historic District |
| St. George Reef Light Station |
| St. Helena Catholic Church |
| St. Helena High School |
| St. Helena Historic Commercial District |
| St. Helena Public Cemetery |
| St. Helena Public Library |
| St. Hilary's Mission Church |
| St. Isidore Catholic Church |
| St. James Park Historic District |
| St. James Square Historic District |
| St. John’s Chapel, Del Monte |
| St. John's Episcopal Church |
| St. John's Episcopal Church |
| St. John's Lutheran Church |
| St. John's Presbyterian Church |
| St. Joseph Catholic Church, Rectory and Cemetery |
| St. Joseph's Basilica |
| St. Joseph's Church and Complex |
| St. Joseph's Home for the Aged |
| St. Joseph's Hospital |
| St. Louis Catholic Church |
| St. Luke’s Episcopal Church |
| St. Matthew's Episcopal Church |
| St. Michael's Episcopal Church |
| Stockton Savings and Loan Society Bank |
| Stoesser Block and Annex |
| Stone House |
| Stoner House |
| Storer House |
| Stoutenburgh House |
| Stow House |
Data from United States Park Service and Wikidata
