Ohio - Significance region: National
| Adena (Thomas Worthington House) |
| Antioch Hall, North And South Halls |
| Beginning Point of the U.S. Public Land Survey |
| Bombeck, Erma, House |
| Brick Quarters Historic District |
| Brownella Cottage and Grace Episcopal Church and Rectory |
| Burchfield Homestead |
| Carew Tower |
| Central Branch, National Home for Disabled Volunteer Soldiers |
| Cincinnati Music Hall |
| Cincinnati Observatory Building |
| Cincinnati Union Terminal |
| Cincinnati Zoo Historic Structures |
| Cleveland Arcade |
| Cleveland Mall |
| Cooke, Jay, House |
| Deeds' Barn |
| DONALD B (towboat) |
| Dunbar, Paul Laurence, House |
| Edison, Thomas Alva, Birthplace |
| Euclid Avenue Presbyterian Church |
| Evans, Wilson Bruce, House |
| Fallen Timbers Battlefield |
| Fort Ancient |
| Fort Meigs |
| Garfield, President James A., Memorial |
| Giddings, Joshua Reed, Law Office |
| Glendale Historic District |
| Glenn, John, Boyhood Home |
| Globe Machine and Stamping Company |
| Goodyear Airdock |
| Greenhills Historic District |
| Gwynne Building |
| Hanford Village George Washington Carver Addition Historic District |
| Harding Tomb |
| Harding, Warren G., House |
| Hatch, George, House |
| Hawthorn Hill |
| Hayes, Rutherford B., House |
| Herron Gymnasium |
| Hoover Farm |
| Hopeton Earthworks |
| Hopewell Mound Group |
| Huffman Field |
| Indian Hills Site |
| James A. Garfield National Historic Site |
| John Sherman Birthplace |
| Johnson Island Civil War Prison and Fort Site |
| Kenyon College |
| Kern Effigy (33WA372) |
| Kettering, Charles F., House |
| King Records Studio Buildings |
| Kirby, James, Mill |
| Kirtland Temple |
| Lakeside Historic District |
| Langston, John Mercer, House |
| Langstroth Cottage |
| Libbey, Edward D., House |
| Lundy, Benjamin, House |
| MAJESTIC |
| Malabar Farm |
| Manasseh Cutler Hall, Ohio University |
| Mariemont Historic District |
| May 4, 1970, Kent State Shootings Site |
| McGuffey, William H., Boyhood Home Site |
| McGuffey, William H., House |
| McKinley, William, Tomb |
| Miami And Erie Canal, Deep Cut |
| Montgomery County Courthouse |
| Morgan, John H., Surrender Site |
| Mound City Group National Monument |
| Muskingum River Navigation Historic District |
| NASA Lewis Research Center-Development Engineering Building & Annex |
| Nela Park |
| Newark Earthworks |
| Oakwood |
| Oberlin College |
| Ohio and Erie Canal |
| Ohio Statehouse |
| Ohio Theatre |
| Old Port Columbus Airport Control Tower |
| Parker, John P., House |
| Parker, John P., House |
| Park Synagogue |
| Pendleton, George Hunt, House |
| Pennsylvania Railroad Depot And Baggage Room |
| People's Federal Savings and Loan Association |
| Perry's Victory and International Peace Memorial |
| Picking, D., And Company |
| Piqua Historical Area State Memorial |
| Plum Street Temple |
| Rickenbacker, Capt. Edward V., House |
| Rombach Place |
| Rush Creek Village Historic District |
| S Bridge, National Road |
| Serpent Mound |
| Seven Ranges Terminus |
| Shaker Square |
| Shaker Village Historic District |
| SHENANDOAH Crash Sites |
Data from United States Park Service and Wikidata
