Massachusetts - Significance region: Local
| Rowley Village Forge Site |
| Roxbury High Fort |
| Roxbury Highlands Historic District |
| Roxbury Presbyterian Church |
| Roynane, Catharine, Three-Decker |
| Rumney Marsh Burying Ground |
| Rural Cemetery and Friends Cemetery |
| Rural Glen Cemetery |
| Russell, Arthur H., House |
| Russell Center Historic District |
| Russell, Charles, House |
| Russell Common |
| Russell Corner Historic District |
| Russell Garrison |
| Russell, Jason House |
| Russell, Philemon, House |
| Russells Mills Village Historic District |
| Russell, Susan, House |
| Russian Cemetery |
| Russia Wharf Buildings |
| Sabbath Day House |
| Sachem Rock Farm |
| Saco-Lowell Shops Housing Historic District |
| Sacred Heart Church Historic District |
| Sacred Heart Parish Complex |
| Sacred Heart School |
| Sadler, Herbert A., House |
| Safety Fund National Bank |
| Sage, Philemon, House |
| Saint Andrew's Chapel |
| Saint John's Episcopal Church |
| Saint Joseph's Home for Working Girls |
| Saint Joseph's Roman Catholic College for Boys |
| Saint Mark's Episcopal Church |
| Salem Lutheran Church |
| Salem Street Burying Ground |
| Salem Willows Historic District |
| Salisbury House |
| Salisbury Mansion and Store |
| Sampson's Folly-Josiah Sampson House |
| Samuel Brown School |
| Samuel Edelman Apartments |
| Sanborn, Rev. Peter, House |
| Sanderson-Clark Farmhouse |
| Sanderson House and Munroe Tavern |
| Sanderson, John, House |
| Sanderson, Julia, Theater |
| Sanderson, Nathan, I, House |
| Sanderson, Nathan, II, House |
| Sands, Hiram, House |
| Sandy Pond School |
| Sanford Whip Factory |
| Sanger, Asa, House |
| Sanger, Richard, III, House |
| Santuit Post Office |
| Sargent-Robinson House |
| Saugus Town Hall |
| Saunders, Daniel, School |
| Saunders-Paine House |
| Saunders, William, House |
| Savin Hill Historic District |
| Sawin-Bullen-Bullard House |
| Sawyer, C. A., House (Second) |
| Sawyer Homestead |
| Saxonville Historic District |
| School Street Barn |
| School Street School |
| School Street School |
| Schuebeler, Charles, House |
| Scott's Woods Historic District |
| Sea Call Farm |
| Searles High School |
| Searles Hill Cemetery |
| Sears, Jacob, Memorial Library |
| Sears Roebuck and Company Mail Order Store |
| Seaside Park |
| Sea Street Historic District |
| Second Cambridge Savings Bank Building |
| Second Church in Boston |
| Second Church of Newton |
| Second O'Shea Building |
| Second Waterhouse House |
| Sever, William, House |
| Sewall-Scripture House |
| S. Gourse & Sons Block |
| Shaarai Torah Synagogue |
| Shadow Brook Farm Historic District |
| Sharon Historic District |
| Sharon House |
| Shattuck, Ralph W., House |
| Shawsheen Cemetery |
| Shaw, Thomas Mott, Estate |
| Shea, Bridget, Three-Decker |
| Sheffield Center Historic District |
| Sheffield Plain Historic District |
| Shelburne Falls Historic District |
| Shelburne Free Public Library |
| "Shell Oil Company ""Spectacular"" Sign" |
| Shepard, Thomas, House |
| Sherborn Center Historic District |
Data from United States Park Service and Wikidata