Massachusetts - Criteria: C (architecture/engineering)
| Santo Christo Church |
| Santuit Historic District |
| Santuit Post Office |
| Sargent-Robinson House |
| Sargent's Pond |
| Saugus Iron Works National Historic Site |
| Saugus Town Hall |
| Saunders, Daniel, School |
| Saunders-Paine House |
| Saunders, William, House |
| Savin Hill Historic District |
| Sawin-Bullen-Bullard House |
| Sawin, Ezekiel, House |
| Sawyer, C. A., House (Second) |
| Sawyer Homestead |
| Sawyer House |
| Saxonville Historic District |
| Sayles, Richard, House |
| Schofield, James, House |
| School Street Barn |
| School Street School |
| School Street School |
| Schuebeler, Charles, House |
| Scituate Light |
| Scott's Woods Historic District |
| Sea Call Farm |
| Seaconnett Mills |
| Searles Castle |
| Searles High School |
| Searles Hill Cemetery |
| Sears' Crescent and Sears' Block |
| Sears, David, House |
| Sears, Jacob, Memorial Library |
| Sears Roebuck and Company Mail Order Store |
| Sears Tower-Harvard Observatory |
| Seaside Park |
| Sea Street Historic District |
| Second Brazer Building |
| Second Cambridge Savings Bank Building |
| Second Church in Boston |
| Second Church of Newton |
| Second O'Shea Building |
| Second Unitarian Church |
| Second Waterhouse House |
| Sever Hall, Harvard University |
| Sewall-Scripture House |
| Shaarai Torah Synagogue |
| Shadow Brook Farm Historic District |
| Shady Hill Historic District |
| Shaker Farm |
| Sharon Historic District |
| Shattuck, Moody, House |
| Shattuck, Ralph W., House |
| Shawsheen Cemetery |
| Shawsheen Village Historic District |
| Shaw, Thomas Mott, Estate |
| Shea, Bridget, Three-Decker |
| Sheffield Center Historic District |
| Sheffield Plain Historic District |
| Shelburne Free Public Library |
| "Shell Oil Company ""Spectacular"" Sign" |
| Shepard Block |
| Shepard, Thomas, House |
| Sherborn Center Historic District |
| Sherburne, Warren E., House |
| Sherman Apartments Historic District |
| Sherman, Eber, Farm |
| Sherman, William B., Farm |
| Shirley Center Historic District |
| Shirley-Eustis House |
| Shirley Shaker Village |
| Shirley Village Historic District |
| Shoe Shop-Doucette Ten Footer |
| Short's Tavern |
| Shrewsbury Historic District |
| Shubert, Sam S., Theatre |
| Shumway Block |
| Sibley-Corcoran House |
| Sidelinger, George A., House |
| Silver Hill Historic District |
| Simcock House |
| Simmons Block |
| Simond, Col. Benjamin, House |
| Simonds, William, House |
| Simpson, Clara, Three-Decker |
| Simpson, Dr. Thomas, House |
| Simpson House |
| Simpson, James E., House |
| Sirna, Anthony and Allison, Studio |
| Six Moon Hill Historic District |
| Skillings Estate House |
| Slade Spice Mill |
| Slater Building |
| Sleepy Hollow Cemetery |
| Slowey, Patrick, House |
| Smith, A. C., & Co. Gas Station |
| Smith Alumnae Gymnasium |
| Smith, Arthur A., Covered Bridge |
| Smith, Bradford, Building |
| Smith, Curtis S., House |
Data from United States Park Service and Wikidata