Massachusetts - Area of significance: Industry
| Newhall, Lucian, House |
| Newton Lower Falls Historic District |
| Newton Upper Falls Historic District |
| New York, New Haven & Hartford Passenger Depot |
| Norad Mill |
| North Andover Center Historic District |
| North Attleborough Town Center Historic District |
| North Becket Village Historic District |
| North Bedford Historic District |
| North Canal |
| North Canal Historic District |
| North Chester Historic District |
| North Easton Historic District |
| North Hadley Historic District |
| North Leverett Historic District |
| Northside Village Historic District |
| Notre Dame Catholic Church |
| Nye, Benjamin, Homestead |
| Oakes, J. J., House |
| O'Hara Waltham Dial Company |
| Old Colony Iron Works-Nesmasket Mills Complex |
| Old Curtisville Historic District |
| Old Mill |
| Old Mill Site Historic District |
| Old Schwamb Mill |
| Old Shipbuilder's Historic District |
| Old Ship Street Historic District |
| Old Town Historic District |
| Old Weir Stove Company |
| Olney Cook Artisan Shop |
| Orange Center Historic District |
| Orlando |
| Osborn House |
| Osgood Bradley Building |
| Osgood Hill |
| Otis Company Mill No. 1 |
| Oxford Main Street Historic District |
| Padanaram Village Historic District |
| Page, Thomas D., House |
| Paine Furniture Building |
| Parker, Harrison, Sr., House |
| Parker, Stillman, House |
| Parkhill Mill |
| Phillips, E. M., House |
| Phillips Woolen Mill |
| Pierce House |
| Pierce Organ Pipe Factory |
| Pilgrim Mills |
| Plimpton, Simon, Farmhouse |
| Plimpton-Winter House |
| Pratt, Miles, House |
| Printers Building, The |
| Provincetown Historic District |
| Punchard, Benjamin House |
| Queguechan Valley Mills Historic District |
| Quincy Granite Railway Incline |
| Reading Municipal Light and Power Station |
| Reed and Barton Complex |
| Rehoboth Village Historic District |
| Renfrew Mill No. 2 |
| Reversible Collar Company Building |
| R. H. Long Company Factory |
| Rhodes, M.M. and Sons Co. |
| Rice, A.H., Silk Mill |
| Richardson, Zachariah, House |
| Richard, Stephen, House |
| Richmond Furnace Historical and Archeological District |
| Rising Paper Mill |
| Ritchie Building |
| Rivulet Mill Complex |
| Robinson Building |
| Rockdale Common Housing District |
| Rocky Neck Historic District |
| Rogers House |
| Rogerson's Village Historic District |
| Rowhouses at 256-274 Haven Street |
| Rowley Village Forge Site |
| Ruggles, Draper, House |
| Russell Center Historic District |
| Russells Mills Village Historic District |
| Sacco-Pettee Machine Shops |
| Sacred Heart Church Historic District |
| Sadler, Herbert A., House |
| Sagamore Mill No. 2 |
| Sagamore Mills No. 1 and No. 3 |
| Sage, Philemon, House |
| Salisbury Factory Building |
| Salisbury Factory Building |
| Sands, Hiram, House |
| Sands, Ivory, House |
| Sandy Neck Cultural Resources District |
| Sanford Spinning Co. |
| Sanford Whip Factory |
| Saugus Iron Works National Historic Site |
| Saxonville Historic District |
| Seaconnett Mills |
| Sea Street Historic District |
| Sewall-Scripture House |
| Sharon House |
| Shawsheen Village Historic District |
Data from United States Park Service and Wikidata
