Massachusetts - Area of significance: Industry
| Shelburne Falls Historic District |
| Shirley Village Historic District |
| Shoe Shop-Doucette Ten Footer |
| Slade Spice Mill |
| Smith Carriage Company District |
| Smith, F.W., Silver Company |
| Smith, Samuel, Tavern Site |
| Smith Shoe Shop |
| South Boston Naval Annex Historic District |
| Southbridge-Sargent Manufacturing District |
| South Common Historic District |
| South Egremont Village Historic District |
| South Lee Historic District |
| South Street Historic District |
| Southwick, Israel, House |
| South Worthington Historic District |
| Spencer Town Center Historic District |
| Spicket Falls Historic District |
| Spot Pond Archeological District |
| Springfield Armory |
| Springfield Steam Power Company Block |
| Springfield Street Historic District |
| Stanton, Jacob, House |
| Staples, Sylvanus N., House |
| Steele, John, House |
| Stevens' Building |
| Stevens Linen Works Historic District |
| St. George's Greek Orthodox Church |
| Stoneholm |
| Stone, Lorenzo R., House |
| Stony Brook-Factory Village Historic District |
| Stoughtonham Furnace Site |
| St. Peter's Roman Catholic Church-St. Mary's School |
| Sturbridge Common Historic District |
| Sullivan, Edward, House |
| Summer Street Historic District |
| Sumner, George, House |
| Swift, D. Wheeler, House |
| Tack Factory, The |
| Taft, Aaron, House |
| Taft, Moses, House |
| Tantiusques Reservation |
| Tapin, Eugene, House |
| Tapley Building |
| Tay, Jesse, House |
| Temple, Joseph, House |
| Tiffany-Leonard House |
| Tobey Homestead |
| Town Brook Historic and Archeological District |
| Town Hall Square Historic District |
| Turner Falls Historic District |
| Twinehurst American Optical Company Neighborhood |
| Two Brothers Rocks-Dudley Road Historic District |
| Union Mills |
| Union Street Railway Carbarn, Repair Shop |
| United Electric Co. Building |
| United Shoe Machinery Corporation Building |
| United Shoe Machinery Corporation Clubhouse |
| United States Watch Company |
| United States Whip Company Complex |
| Valentine Soap Workers Cottage |
| Valentine Soap Workers Cottage |
| Vamp Building |
| Van Deusen, H. M., Whip Company |
| Vermont Building |
| Vickery-Baylies House |
| Wachusett Shirt Company |
| Wade, John, House |
| Wakefield Rattan Co. |
| Wakefield Upper Depot |
| Walker Body Company Factory |
| Waltham Gas Light Company |
| Wamesit Canal-Whipple Mill Industrial Complex |
| Wampanoag Mills |
| Wamsutta Mills |
| Waquoit Historic District |
| Ware Millyard Historic District |
| Ware Paper Mill |
| War Memorial Park |
| Washburn and Moen North Works District |
| Washington Street Historic District |
| Washington Street Shoe District |
| Wason-Springfield Steam Power Blocks |
| Water Shops Armory |
| Watertown Arsenal Historic District |
| Watson, Newell & Company Factory |
| Waucantuck Mill Complex |
| Wellington Piano Case Company Building |
| Wells, George B. and Ruth D., House |
| Wells, H. C., Double House |
| Wells House |
| Wells, John M., House |
| Wenham Historic District |
| Wesson, Franklin, House |
| West Barnstable Village-Meetinghouse Way Historic District |
| West Brookfield Center Historic District |
| West Chesterfield Historic District |
| Westfield Whip Manufacturing Company |
| West Gardner Square Historic District |
| West Main Street Historic District |
Data from United States Park Service and Wikidata
