California - Area of significance: Architecture
| Santa Clara Depot |
| Santa Clara Verein |
| Santa Cruz Downtown Historic District |
| Santa Fe Depot |
| Santa Fe Federal Savings and Loan Association |
| Santa Fe Freight Depot |
| Santa Fe Passenger and Freight Depot |
| Santa Fe Passenger Depot |
| Santa Fe Railway Passenger and Freight Depot |
| Santa Margarita Ranchhouse |
| Santa Monica Civic Auditorium |
| Santa Paula Hardware Company Block-Union Oil Company |
| Santa Rosa Island Archeological District |
| Santora Building |
| Sara-Thel Court |
| Saratoga Foothill Club |
| Sargent, B. V., House |
| Sather Gate and Bridge |
| Sather Tower |
| Saticoy Southern Pacific Railroad Depot |
| Sawyers Bar Catholic Church |
| Schaffer, J.W. House |
| Schindler, R. M., House |
| Schoenstein and Company Pipe Organ Factory |
| Schonchin Butte Fire Lookout |
| Schorlig House |
| Scott, Hiram D., House |
| Scripps College for Women |
| Scully Ranch |
| Seal Beach City Hall |
| Second and Howard Streets District |
| Second Church of Christ Scientist |
| Second Church of Christ, Scientist |
| Security Bank and Trust Company Building |
| Security-First National Bank of Los Angeles |
| Security Trust and Savings |
| Security Trust and Savings Building |
| Semorile Building |
| Senior Hall |
| Senior Officers Quarters Historic District, Yerba Buena Island |
| Sequoia Union High School |
| Serrano, Jose, Adobe |
| Sexton, Joseph and Lucy Foster, House |
| Shadelands Ranch House |
| Shady Point |
| Shaffer, Charles A., House |
| Shannon-Williamson Ranch |
| Shasta State Historic Park |
| Shaw House |
| Shell Gas Station |
| Shiloh Baptist Church |
| Shorty Lovelace Historic District |
| Sieroty House |
| Sierra County Sheriff's Gallows |
| Sierra Railway Shops Historic District |
| Sierraville School |
| Silberstein Park Building |
| Simi Adobe-Strathearn House |
| Simmons, William Adam, House |
| Simon's, M. H., Undertaking Chapel |
| Simpson-Vance House |
| Sinatra, Frank, House |
| Singer Building |
| Six Sisters-Lawn Way Historic District |
| Smiley Park Historic District |
| Smith and Clark Brothers Ranch and Grounds |
| Smith, Ernest W., House |
| Smith Estate |
| Smith, Maurice, and Dinah Shore House |
| Smith-Tuthill Funeral Parlors |
| Smith, Williams, House |
| SMUD Headquarters Building |
| Snow Creek Ski Hut |
| Sonoma Depot |
| Sonoma Grammar School |
| Sonoma Plaza |
| Sonoma State Home-Main Building |
| Sonoma Valley Woman's Club |
| South Berkeley Community Church |
| South Bonnie Brae Tract Historic District |
| Southern California Gas Company Complex |
| Southern Counties Gas Co. |
| Southern Hotel |
| Southern Pacific 16th Street Station and 16th Street Tower |
| Southern Pacific Company Hospital Historic District |
| Southern Pacific Depot |
| Southern Pacific Depot |
| Southern Pacific Depot |
| Southern Pacific Passenger Depot |
| Southern Pacific Railroad Bayshore Roundhouse |
| Southern Pacific Railroad Company's Sacramento Depot |
| Southern Pacific Railroad Depot, Whittier |
| Southern Pacific Railroad Station |
| Southern Pacific Train Depot |
| South Hall |
| South Marengo Historic District |
| South of Campus Neighborhood |
| South San Francisco Opera House |
| South Serrano Avenue Historic District |
| Southwest Museum |
Data from United States Park Service and Wikidata
