South Carolina - Significance region: Local
| Hermon Presbyterian Church |
| Herndon Terrace |
| Hester Store |
| Hickman Mill Historic District |
| Hickory Valley Historic District |
| Hicks, Wade Hampton, House |
| Hicks, Zeno, House |
| Highland Park Manufacturing Plant and Cotton Oil Complex |
| Hightower Hall |
| Hill Complex Historic District |
| Hillside |
| Hill, W. L., Store |
| Hite, John Jacob, Farm |
| H. L. HUNLEY (submarine) |
| Hoffman, George P., House |
| Holliday, J. W., Jr., House |
| Holly Hill Downtown Historic District |
| Holly Springs School |
| Holman, J. B., House |
| Holman’s Barber Shop |
| Holy Cross Faith Memorial School |
| Home National Bank |
| Hope Rosenwald School |
| Hopewell Presbyterian Church and Hopewell Cemetery |
| Hopewell Rosenwald School |
| Hopkins Family Cemetery |
| Hopkins Farm |
| Horry County Courthouse |
| Host of America Motel |
| Hotel Albert Commercial Block |
| Hotel Eutaw |
| Hotel Keturah |
| Hotel Oregon |
| House of Peace Synagogue |
| Houser, David, House |
| Howard Junior High School |
| Hudson, Nelson, House |
| Hurricane Tavern |
| Hutchinson House |
| Immanuel School |
| Imperial Hotel |
| Inman Mills |
| Irby, Dr. William Claudius, House |
| Irby-Henderson-Todd House |
| Irene Mill Finishing Plant |
| Isaqueena |
| Jackson Street Freedman's Cottages |
| James Building |
| James, Louie, House |
| Jamestown Historic District |
| Jefferies House |
| Jennings-Brown House |
| Jeter, Gov. Thomas B., House |
| John's Island Presbyterian Church |
| Johnston Historic District |
| Jones, A. C., House |
| Judson Mill |
| Keil Farm |
| Kelley, Jacob, House |
| Kendall Mill Historic District |
| Kennedy Street School |
| Ketchin Building |
| Kilgore, Josiah, House |
| Kinard House |
| King Cemetery |
| Kingston Presbyterian Church |
| Kingston Presbyterian Church Cemetery |
| Kingstree Historic District |
| Knights of Wise Men Lodge |
| Koon, John Jacob Calhoun, Farmstead |
| Kumler Hall |
| Lady's Island Bridge |
| Lake City Downtown Historic District |
| Lancaster Downtown Historic District |
| Lancaster Presbyterian Church |
| Lander College Old Main Building |
| Landsford Plantation House |
| Latimer High and Elementary School |
| Latta Downtown Historic District |
| Latta Historic District No. 1 |
| Latta Historic District No. 2 |
| Laurel Bay Plantation |
| Laurelwood Cemetery |
| Laurens County Courthouse |
| Laurens Historic District |
| Lawson's Pond Plantation |
| Lawton, John, House |
| Lawton-Seabrook Cemetery |
| Lawtonville Baptist Church |
| Leesville College Historic District |
| Leevy’s Funeral Home |
| Lenoir Store |
| Lewisfield Plantation |
| Lexington County Courthouse |
| Liberty Colored High School |
| Lide, Evan J., House |
| Lide, John W., House |
| Lincoln High School |
| Lindsay Cemetery |
| Little Mountain Historic District |
Data from United States Park Service and Wikidata