South Carolina - Role: Building
| Ramer, Ralph John, House |
| Rankin-Harwell House |
| Rasor and Clardy Company Building |
| Rauch, Charlton, House |
| Rawl-Couch House |
| Rawl, David, House |
| Rawl, John Jacob, House |
| Read Building |
| Redcliffe |
| Red Doe |
| Reidville Academy Faculty House |
| Reighley, Ike, House |
| Rembert Church |
| Republic Theater |
| Retreat Rosenwald School |
| Rhett, Robert Barnwell, House |
| Richardson-Godbold House |
| Richardson, J.C., House |
| Richardson, Lawrence L., House |
| Richland Cotton Mill |
| Richland Presbyterian Church |
| Ridge Hill High School |
| Robb, William, House |
| Robertson-Easterling-McLaurin House |
| Robertson, William, House |
| Robertville Baptist Church |
| Robinson-Hiller House |
| Rock Hill Body Company |
| Rock Hill Cotton Factory |
| Rogers, Paul H., House |
| Rogers, William, House |
| Roper House Complex |
| Roper, Robert William, House |
| Rose Hill |
| Rose Hill Plantation House |
| Roselawn |
| Rosemary Hall |
| Rose, Thomas, House |
| Roseville Plantation |
| Ruff's Chapel |
| Rural Hall Plantation House |
| Rural Point |
| Russell-Heath House |
| Russell House |
| Russell, Nathaniel, House |
| Ruth's Beauty Parlor |
| Rutledge, Edward, House |
| Rutledge, Gov. John, House |
| Sadler Store |
| Saint Thomas' Protestant Episcopal Church |
| Salem Black River Presbyterian Church |
| Salmon, George, House |
| Saluda Apartments |
| Saluda Theatre |
| Sandy Island School |
| Sapp, William Harrison, House |
| Scarborough, Henry Lee, House |
| Scheper, F.W., Store |
| Schuyler Apartments |
| Scott, Claudius, Cottage |
| Scott House |
| Scott’s Branch High School |
| Seaboard Air Line Railway Depot |
| Seaboard Air Line Railway Depot in McBee |
| Seaboard Air Line Railway Depot in Patrick |
| Seabrook, William, House |
| Seacoast Packing Company |
| Seashore Farmers' Lodge No. 767 |
| Seaside Plantation |
| Seaside Plantation House |
| Seaside School |
| Seay, Jammie, House |
| Self, James C., House |
| Selkirk Farm |
| Seneca Cotton Mill |
| Senn's Grist Mill-Blacksmith Shop-Orange Crush Bottling Plant |
| Settlemyer House |
| Sheriff Mill Complex |
| Shiloh Methodist Church |
| Shirley, Obediah, House |
| Sidney Park Colored Methodist Episcopal Church |
| Siloam School |
| Simkins, Modjeska Monteith, House |
| Simmons-Edwards House |
| Simmons-Harth House |
| Simmons, James Stocker, House |
| Simmons, Robert, House |
| Simpsonville Baptist Church |
| Simpson, William Dunlap, House |
| Sims High School |
| Sinclair Service Station |
| Sitgreaves House |
| Sixth Naval District Training Aids Library |
| Slave Houses, Gregg Plantation |
| Smalls, Robert, House |
| Smalls, Robert, School |
| Smith Barn |
| Smith-Cannon House |
| Smith, J. Warren, House |
| Smith's Tavern |
Data from United States Park Service and Wikidata
