South Carolina - Role: Building
| Oak Grove |
| Oak Island |
| Oakland Mill |
| Oakland Plantation |
| Oakland Plantation |
| Oakland Plantation House |
| Oaks, The |
| Oakwood |
| Ocean Forest Country Club |
| Ocean Grove School |
| Oconee County Courthouse |
| Oconee Station and Richards House |
| Octagon House |
| O'Donnell House |
| Old Batesburg Grade School |
| Old Batesburg-Leesville High School |
| Old Bethel United Methodist Church |
| Old Brass |
| Old Colleton County Jail |
| Old Courthouse |
| Old Courthouse |
| Old Ebenezer Church |
| Old Greenwood High School |
| Old Horry County Courthouse |
| Old House Plantation |
| Old Marine Hospital |
| Old Market Building |
| Old Pickens Jail |
| Old Pickens Presbyterian Church |
| Old Presbyterian Church |
| Old Slave Mart |
| Old Stone Church and Cemetery |
| Old Stone House |
| Oliver, Peter M. and Alice, House |
| Olympia Armory |
| Olympia Mill |
| Olympia Mill School |
| Olympia Union Hall |
| Orangeburg County Fair Main Exhibit Building |
| Orangeburg County Jail |
| Orange Grove |
| Orr, Dr. Samuel Marshall, House |
| Otranto Plantation |
| Owen Building |
| Owings, John Calvin, House |
| Pacific Community Association Building |
| Pacolet Mill Office |
| Pacolet Mills Cloth Room and Warehouse |
| Padgett's Creek Baptist Church |
| Palmetto Building |
| Palmetto Compress and Warehouse Company Building |
| Palmetto Theater |
| Palmetto Theatre |
| Parker High School Auditorium |
| Parrish's Motor Court |
| Patrick, Dr. John B., House |
| Peeples, Hattie J., House |
| Pegues Place |
| Pelzer Presbyterian Church |
| People's Free Library of South Carolina |
| People's National Bank Building |
| Perry-McIlwain-McDow House |
| Peter's Point Plantation |
| Phelps House |
| Phinney, James, House |
| Pickens House |
| Piedmont Mill Stores Building |
| Pine Grove Rosenwald School |
| Pineland, The |
| Pine Street Elementary School |
| Pinewood Depot |
| Pleasant Grove School |
| Pleasant Hill Consolidated School |
| Pleasant Inn |
| Poe Hardware and Supply Company |
| Poinsett Hotel |
| Pomaria |
| Pompion Hill Chapel |
| Port Royal School |
| Powder Magazine |
| Powell, J. Davis, House |
| Poynor Junior High School |
| Presbyterian Manse |
| Presqui'ile |
| Pressley, Colonel John Gotea, House |
| Price, George R., House |
| Price, Raymond, House |
| Price's Mill |
| Price's Post Office |
| Prince George Winyah Church (Episcopal) and Cemetery |
| Progressive Club, The |
| Prospect Hill |
| Providence Methodist Church |
| Puritan Farm |
| Quattlebaum, C. P., House |
| Quattlebaum, C. P., Office |
| Quattlebaum, Paul, House |
| Quillen, Robert, Office and Library |
| Quinby Plantation House-Halidon Hill Plantation |
| Rainey, Joseph H., House |
Data from United States Park Service and Wikidata
