South Carolina - Area of significance: Politics/Government
| Hibernian Hall |
| Historic Camden Revolutionary War Restoration |
| Hopsewee |
| Horry County Courthouse |
| Huger, Cleland Kinloch and Burnet R. Maybank, House |
| Irby-Henderson-Todd House |
| Jasper County Courthouse |
| Jeter, Gov. Thomas B., House |
| John's Island Presbyterian Church |
| Joye Cottage |
| Kincaid-Anderson House |
| Lancaster County Courthouse |
| Laurens County Courthouse |
| Lee County Courthouse |
| Leevy’s Funeral Home |
| Lewis Inn |
| Lorick, Preston C., House |
| Lowndes Grove |
| Magnolia |
| Mansfield Plantation |
| Marion Historic District |
| McCormick County Courthouse |
| McCormick County Office Building |
| McLaurin House |
| Means-Gage House |
| Means House |
| Medway |
| Meetze, Maj. Henry A., House |
| Merridun |
| Middleton Place |
| Midway Plantation |
| Millford Plantation |
| Millwood |
| Mower, George, House |
| Mt. Zion Institute High School |
| Mulberry Plantation (Chesnut House) |
| Nance, Frederick, House |
| Nicholson, James, House |
| Nickels-Milam House |
| Ninety Six National Historic Site |
| North Carolina-South Carolina Cornerstone |
| Oakland Plantation |
| Old Batesburg-Leesville High School |
| Old Dorchester |
| Old Horry County Courthouse |
| Old Market Building |
| Old Pickens Jail |
| Old Presbyterian Church |
| Old Stone Church and Cemetery |
| Orangeburg Downtown Historic District |
| Pegues Place |
| Pendleton Historic District |
| Penn Center Historic District |
| Plane Hill |
| Poinsett State Park Historic District |
| Pomaria |
| Powder Magazine |
| Puritan Farm |
| Rainey, Joseph H., House |
| Randolph Cemetery |
| Rankin-Harwell House |
| Rhett, Robert Barnwell, House |
| Richardson-Godbold House |
| Richardson, Lawrence L., House |
| Robert Mills Manor |
| Roper House Complex |
| Rose Hill |
| Rural Point |
| Rutledge, Edward, House |
| Rutledge, Gov. John, House |
| Saluda Apartments |
| Secessionville Historic District |
| Sheldon Church Ruins |
| Simpson, William Dunlap, House |
| Singleton's Graveyard |
| Smalls, Robert, House |
| Smith-Cannon House |
| Snee Farm-Charles Pinckney National Historic Site |
| South Carolina Archives Building |
| South Carolina Governor's Mansion |
| South Carolina Statehouse |
| South Carolina State Library |
| South Harper Historic District |
| South Main Historic District |
| Springfield Plantation House |
| St. Andrews Episcopal Church |
| Stateburg Historic District |
| St. Mark's Church |
| Sturkey, M. L. B., House |
| Sumter County Courthouse |
| Sumter Historic District |
| Sumter Town Hall-Opera House |
| Table Rock Civilian Conservation Corps Camp Site |
| Table Rock State Park Historic District |
| Tanglewood Plantation |
| Union National Bank Building |
| United States Post Office and Court House |
| United States Post Office and Court House |
| US Court House-Aiken, South Carolina |
| U.S. Highway 25 |
Data from United States Park Service and Wikidata
