South Carolina - Area of significance: Politics/Government
| U.S. Post Office |
| U.S. Post Office and Courthouse |
| US Post Office and Courthouse |
| Valencia |
| Vander Horst, Arnoldus, House |
| Veterans Administration Regional Office |
| Wade Hampton State Office Building |
| Waxhaw Presbyterian Church Cemetery |
| Welsh Neck-Long Bluff-Society Hill Historic District |
| West Gervais Street Historic District |
| White Church |
| White, Elizabeth, House |
| Whitehall |
| Whitehall |
| White House |
| White, William Elliott, House |
| Williams-Ball-Copeland House |
| Willtown Bluff |
| Wilson House |
| Wilson, Thomas Woodrow, Boyhood Home |
| Winnsboro Historic District |
| Witherspoon-Hunter House |
| Woodburn |
| York County Courthouse |
| York Historic District |
| Young, Virginia Durant, House |
| Zion Baptist Church |
Data from United States Park Service and Wikidata
