South Carolina - Area of significance: Politics/Government
| Abbeville County Courthouse |
| Abbeville Historic District |
| Aiken County Hospital |
| Aiken, Gov. William, House |
| Alexander-Hill House |
| Allendale County Courthouse |
| Allison Plantation |
| Anchorage, The |
| Anderson Downtown Historic District |
| Anderson Historic District |
| Annandale Plantation |
| Arcadia Plantation |
| Ashley Hall Plantation |
| Ashwood School Gymnasium and Auditorium |
| Bamberg City Hall |
| Banks, Col. J. A., House |
| Banksia Hall |
| Barber House |
| Barnwell-Gough House |
| Beaufort Historic District |
| Bennett, Gov. Thomas, House |
| Berly, William, House |
| Bleak Hall Plantation Outbuildings |
| Bonham House |
| Boozer, Lemuel, House |
| Borough House Plantation |
| Brattonsville Historic District |
| Brookgreen Gardens |
| Bruce, Donald, House |
| Building at 1210-1214 Main Street |
| Burt, Armistead, House |
| Butler Family Cemetery |
| Cainhoy Historic District |
| Caldwell-Hampton-Boylston House |
| Calhoun County Courthouse |
| Calhoun, John C., State Office Building |
| Calhoun, Patrick, Family Cemetery |
| Cantey, Zachariah, House |
| Carroll, Chancellor James P., House |
| Carroll Place |
| Cauthen, Dr. William Columbus, House |
| Cedar Bluff |
| Charleston Historic District |
| Charleston's French Quarter District |
| Cheraw Historic District |
| Chesnut Cottage |
| Chicora Wood Plantation |
| Christ Church |
| Church of the Holy Apostles Rectory |
| City of Camden Historic District |
| Civilian Conservation Corps Quarry No. 1 and Truck Trail |
| Civilian Conservation Corps Quarry No. 2 |
| Clarendon County Health Center and Office Building |
| Cleveland Law Range |
| Coateswood |
| Coffin Point Plantation |
| Cohasset |
| Colleton County Courthouse |
| Colonial Village Apartments |
| Columbia City Hall |
| Columbia Historic District I |
| Columbia Historic District II |
| Confederate Printing Plant |
| """Congarees"" Site" |
| Conway Downtown Historic District |
| Culp House |
| Dantzler, Col. Olin M., House |
| Darby Plantation |
| Dawkins, Judge Thomas, House |
| Derham, John P., House |
| Dillon County Courthouse |
| Donaldson, T. Q., House |
| Earle Town House |
| Eden Hall |
| Edgefield Historic District |
| Ellicott Rock |
| Ensor-Keenan House |
| Evans-Russell House |
| Exchange and Provost |
| Fairfield Plantation |
| Federal Land Bank Building |
| First Baptist Church |
| Fort Hill |
| Fort Johnson/Powder Magazine |
| Fort Sumter National Monument |
| Gravel Hill Plantation |
| Green's Funeral Home and Ambulance Service |
| Greenville County Courthouse |
| Greer Depot |
| Hagood-Mauldin House |
| Hamer Hall |
| Hamer, James W., House |
| Hampton County Courthouse |
| Hampton-Preston House |
| Harrietta Plantation |
| Hart House |
| Hartsville Community Center-Hartsville Community Market |
| Hartsville Post Office |
| Hendrix, Henry Franklin, House |
| Heyward-Washington House |
Data from United States Park Service and Wikidata
