Pennsylvania - Significance region: National
| 1724 Chester Courthouse |
| Academy of Music |
| Acheson, Edward G., House |
| Alfred Newton Richards Medical Research Laboratories and David Goddard Laboratories Buildings |
| Allegheny Cemetery |
| Allegheny County Courthouse and Jail |
| Allegheny Portage Railroad National Historic Site |
| Allegheny Post Office |
| Aluminum Research Laboratories |
| American Baptist Publication Society |
| American Philosophical Society Hall |
| Andalusia |
| Anderson, Marian, House |
| Antes, Henry, House |
| Arch Street Friends Meeting House |
| Arch Street Opera House |
| Arch Street Presbyterian Church |
| Ashley Planes |
| Askew Bridge |
| Athenaeum of Philadelphia |
| Augustus Lutheran Church |
| Barns-Brinton House |
| Bartram, John, House |
| Bedford Springs Hotel Historic District |
| Beggarstown School |
| Bethlehem Steel Lehigh Plant Mill #2 Annex |
| Beth Sholom Synagogue |
| Billmeyer, Daniel, House |
| Billmeyer House |
| Billmeyer, Michael, House |
| Birchrunville General Store |
| Birmingham Friends Meetinghouse and School |
| Black Moshannon State Park Day Use District |
| Black Moshannon State Park Family Cabin District |
| Black Moshannon State Park Maintenance District |
| Boal Mansion |
| Boat House Row |
| Bomberger's Distillery |
| Boone, Daniel, Homestead Site and Bertolet Cabin |
| Bost Building |
| Bradford, David, House |
| Bradford Friends Meetinghouse |
| Brandywine Battlefield |
| Brinton's Mill |
| Brown, John, House |
| Bryn Athyn Historic District |
| Bryn Mawr |
| Bryn Mawr Hotel |
| Buchanan, James, House |
| Buckingham Friends Meeting House |
| Buhl Building |
| Bushy Run Battlefield |
| Calvary Episcopal Church |
| Cambria Iron Company |
| Cameron Estate |
| Carbon County Section of the Lehigh Canal |
| Carlisle Indian School |
| Carl Mackley Houses |
| Carnegie Free Library Of Braddock |
| Carnegie Institute and Library |
| Carpenters' Hall |
| Carrie Blast Furnace Number 6 and 7 |
| Carson, Rachel, House |
| Cashier's House |
| Cathedral of Learning |
| Cathedral of Saints Peter and Paul |
| Cedarcroft |
| Centennial National Bank |
| Central Bethlehem Historic District |
| Central Market |
| Chadds Ford Historic District |
| Chamounix |
| Chapman, John, House |
| Chatham Village Historic District |
| Cherry Springs Picnic Pavilion |
| Chester Springs Historic District |
| Chestnut Hill Historic District |
| Christ Church |
| Christ Church Burial Ground |
| Church of St. James the Less |
| Church of the Holy Trinity |
| Clear Creek State Park Day Use District |
| Clear Creek State Park Family Cabin District |
| Cliffs, The |
| Cliveden (Chew House) |
| College of Physicians of Philadelphia Building |
| Colonial Germantown Historic District |
| Colton Point State Park |
| Coltrane, John, House |
| Combination Baggage and Mail Car No. 5403 |
| Commandant's Quarters |
| Compton and Bloomfield |
| Conestoga Town |
| Consolidation Freight Locomotive No. 1187 |
| Consolidation Freight Locomotive No. 2846 |
| Consolidation Freight Locomotive No. 7688 |
| Continental Powder Works at French Creek |
| Cook, Col. Edward, House |
| Cook Forest State Park Indian Cabin District |
| Cook Forest State Park River Cabin District |
Data from United States Park Service and Wikidata
