Pennsylvania - Significance region: Local
| Donaldson, Widow, Place |
| Donaldson, William, House |
| Dorneyville Crossroad Settlement |
| Dorrance Mansion |
| Dorsey, Joseph, House |
| Dougherty, Edward, House |
| Dougherty, Philip, House |
| Dougherty, Philip, Tavern |
| Douglas, John S., House |
| Douglass, George, House |
| Douglass, John, House |
| Downer Tavern |
| Downingtown Log House |
| Downtown Altoona Historic District |
| Downtown Indiana Historic District |
| Downtown Wayne Historic District |
| Drake Hotel |
| Drake Log Cabin |
| Dreibelbis, Joel, Farm |
| Dreibelbis Mill |
| Drexel Development Historic District |
| Drexel, Francis M., School |
| Dritt Mansion |
| Drovers Inn |
| Drueding Brothers Company Building |
| Dubois Historic District |
| Dunbar-Creigh House |
| Dunbar, Paul Lawrence, School |
| Dungan, Pugh, House |
| Dunlap, Thomas, School |
| Dunlap, William B., Mansion |
| Duquesne Brewing Company |
| Duquesne Incline |
| Durham, Thomas, School |
| Dusmal House |
| Dutch Corner Historic Agricultural District |
| Dyerstown Historic District |
| Dykeman's Spring |
| Eagle Hotel |
| Eagle Tavern |
| Eakin, John, Farm |
| East Berlin Historic District |
| East Bradford Boarding School for Boys |
| East Carson Street Historic District |
| East Center City Commercial Historic District |
| East Lancaster Avenue Historic District |
| East Liberty Market |
| East, Nicholas, House |
| Easton Cemetery |
| Easton Historic District |
| Easton House |
| East Stroudsburg Railroad Station |
| East Washington Historic District |
| East York Historic District |
| E.A. Wright Bank Note Company Building |
| Ebensburg Historic District |
| Eberhardt and Ober Brewery |
| Eby Shoe Corporation |
| Eckman, Sam, Covered Bridge No. 92 |
| Edelman Schoolhouse |
| Eden Cemetery |
| Edgemont |
| Edgewood |
| Edmunds, Henry R., School |
| Edward Corner Marine Merchandise Warehouse |
| Egg Hill Church |
| Ehrenhardt, Jacob Jr., House |
| Eichelberger High School |
| Eisenlohr-Bayuk Tobacco Historic District |
| Elder, Abraham, Stone House |
| Elkins Railroad Station, Philadelphia and Reading Railroad |
| Elmridge |
| Elmwood Park Historic District |
| Elverson Historic District |
| Elverson, James, Jr., School |
| Ely, Joshua, House |
| Embassy Theatre |
| Embreeville Historic District |
| Emig Mansion |
| Emlen, Eleanor Cope, School of Practice |
| Engine Company No. 29 |
| Englehardt, John, Homestead |
| Ephrata Commercial Historic District |
| Equinunk Historic District |
| Equitable Trust Building |
| Ercildoun Historic District |
| Erie Federal Courthouse and Post Office |
| Erie Masonic Temple |
| Erie Trust Company Building |
| Erpff, Philip, House |
| Erskine Covered Bridge |
| Estey Hall |
| Etters Bridge |
| Evans, Ann Cunningham, House |
| Evans, Benjamin, House |
| Evans, William and Mordecai, House |
| Everett Historic District |
| Evergreen Hamlet |
| Everhart, William, Buildings |
| Everhart, William, House |
Data from United States Park Service and Wikidata
