Pennsylvania - Significance region: Local
| Cook, Anthony Wayne, Mansion |
| Cooke, Jay, Junior High School |
| Cookes House |
| Coopersburg Historic District |
| Cope's Bridge |
| Coraopolis Railroad Station |
| Corbin Bridge |
| Corbley, John, Farm |
| Corker Hill |
| Cornwall & Lebanon Railroad Station |
| Corry Historic District |
| Corson, Alan W., Homestead |
| Cotton and Maple Streets School |
| Coudersport and Port Allegany Railroad Station |
| Coudersport Historic District |
| Cox, Hewson, House |
| Craft, Gershom, House |
| Craig Family Cemetery |
| Cramond |
| Craven Hall |
| Crawford Covered Bridge |
| Crawford, John Minor, House |
| Crawford, William, House |
| Creasyville Covered Bridge |
| Cree, William, House |
| Creighton, Thomas, School |
| Crook Farm |
| Crosley-Garrett Mill Workers' Housing, Store and Mill Site |
| Crossan, Kennedy, School |
| Crown Can Company Building |
| Crozer, George K., Mansion |
| Crozer, John P., II, Mansion |
| Culbertson-Harbison Farm |
| Cumberland Valley Railroad Station and Station Master's House |
| Cuppett's Covered Bridge |
| Curtin Village |
| Curtis and Jones Company Shoe Factory |
| Curtis Arboretum |
| Dager-Wonsettler Farmstead |
| Dale, Felix, Stone House |
| Dale, Samuel F., House |
| Damascus Historic District |
| Danley Covered Bridge |
| Danville Historic District |
| Danville West Market Street Historic District |
| Darby Meeting |
| Darrah, Lydia, School |
| Dauphin County Bridge No. 27 |
| Dauphin County Courthouse |
| Davies, Edward, House |
| Davies House |
| Davis Covered Bridge |
| Davis, Daniel, House and Barn |
| Davis, David, Farm |
| Davis, Horn, Overholtzer Bridge |
| Dawesfield |
| Dawson Historic District |
| Day Covered Bridge |
| Decker's Chapel |
| Deer Creek Bridge, Stewartstown Railroad |
| Deery Family Homestead |
| Deffenbaugh Site (36FA57) |
| Defibaugh Tavern |
| DeHaven, Harry, House |
| Deisher, H. K., Knitting Mill |
| Delaware County National Bank |
| Delaware, Lackawanna and Western Railroad Station |
| Delaware, Lackawanna and Western Railroad Water Gap Staion |
| Delaware Station of the Philadelphia Electric Company, The |
| Delbar Products, Inc. |
| Delmar Apartments |
| Delta Historic District |
| Delta Trestle Bridge, Maryland and Pennsylvania Railroad |
| Dent Hardware Company Factory Complex |
| Derbydown Homestead |
| Derrow, Margaret, House |
| Derry Session House and Enclosure |
| Deutschtown Historic District |
| D & H Canal Co. Office |
| Diamond Silk Mill |
| Dick Building |
| Dickson Tavern |
| Dickson Works |
| Diehl, George, Homestead |
| Diehls Covered Bridge |
| Dill's Tavern |
| Dilworth Elementary School |
| Dime Bank Building |
| Dimeling Hotel |
| Dime Savings and Trust Company |
| Dingman's Ferry Dutch Reformed Church |
| Disston, Hamilton, School |
| Disston, Mary, School |
| Doak-Little House |
| Dobbins, Murrell, Vocational School |
| Dobson, James, School |
| Dobson Mills |
| Doe Run Village Historic District |
| Dohner, Michael, Farmhouse |
| Dolington Village Historic District |
Data from United States Park Service and Wikidata
