Pennsylvania - Criteria: C (architecture/engineering)
| Speakman No. 2, Mary Ann Pyle Bridge |
| Special Troops Armory |
| Speedwell Forge Mansion |
| Sperling Building |
| Spicker, Peter, House |
| Spinner House |
| Sprenger Brewery |
| Springdale Farm |
| Springdale Historic District |
| Springdale Historic District |
| Springer Farm |
| Springfield Public School |
| Spring Garden District |
| Spring Garden School No. 1 |
| Spring Garden School No. 2 |
| Spring Grove Borough Historic District |
| Spring Grove Farm and Distillery |
| Spring Grove Forge Mansion |
| Spring Mill Complex |
| Springton Manor Farm |
| Springtown Historic District |
| Spring Valley Historic District |
| Spruce Creek Rod and Gun Club |
| Square Tavern |
| SS UNITED STATES (Steamship) |
| Stanley |
| Stanley Theater and Clark Building |
| St. Anthony de Padua Parish School |
| St. Anthony Hall House |
| Stanton, Edwin M., School |
| Star Barn Complex |
| Star Junction Historic District |
| Starlight Station, New York, Ontario, and Western Railway |
| Starrucca Viaduct |
| State Theatre |
| Stauffer, Christian, House |
| Stauffer, Dr. B., House |
| St. Augustine's Catholic Church |
| St. Boniface Roman Catholic Church |
| St. Clement's Protestant Episcopal Church |
| St. David's Church and Graveyard |
| Steckel, Daniel, House |
| Steelton High School |
| Stegmaier Brewery |
| Steinman Hardware Store |
| Stein Mill |
| St. Elizabeth's Convent |
| Stenton |
| Stephens, Linton, Covered Bridge |
| Stephenson-Campbell House |
| Sterrett Sub-District School |
| Stevens High School |
| Stevens School |
| Stewart, Gen. Thomas J., Memorial Armory |
| Stewart, John, Houses |
| Stewartstown Engine House, Stewartstown Railroad |
| Stewartstown Railroad Station |
| St. Gabriel's Catholic Parish Complex |
| St. Gabriel's Episcopal Church, Old |
| St. George's Methodist Church |
| St. Gertrude Roman Catholic Church |
| Stillwater Covered Bridge No. 134 |
| Stirling |
| Stirling, Maj. Gen. Lord, Quarters |
| St. James Episcopal Church |
| St. James Hotel |
| St. John's Church |
| St. John's Evangelical Lutheran Church |
| St. John the Baptist Ukranian Catholic Church |
| St. John the Evangelist Roman Catholic Church and School Building |
| St. Joseph's House for Homeless Industrious Boys |
| St. Lukes Episcopal Church |
| St. Mark's Episcopal Church |
| St. Mark's Episcopal Church |
| St. Mary's Covered Bridge |
| St. Mary's Episcopal Church |
| St. Marys Historic District |
| St. Michael's Protestant Episcopal Church, Parish House and Rectory |
| St. Nicholas Byzantine Catholic Church |
| St. Nicholas Croatian Church |
| Stoddartsville Historic District |
| Stoever, John Casper, Log House |
| Stone Arch Road Bridge, Stewartstown Railroad |
| Stonehaven |
| Stoner, Samuel, Homestead |
| Stonorov, Oskar G., House |
| Stotesbury Club House |
| Stouchsburg Historic District |
| Stout, Isaac, House |
| Stover, Isaac, House |
| Stover Mill |
| Stoystown Historic District |
| St. Paul's Church |
| St. Paul's Episcopal Church |
| St. Paul's Union Church and Cemetery |
| St. Peter's Cathedral Complex |
| St. Peter's Church |
| St. Peter's Church |
| St. Peter's Church in the Great Valley |
| St. Peter's Episcopal Church and Rectory |
Data from United States Park Service and Wikidata