Pennsylvania - Area of significance: Commerce
| Allegheny Aqueduct |
| Allegheny Portage Railroad National Historic Site |
| Allegheny Second Ward Industrial Historic District |
| Allentown National Bank |
| Allgates |
| Ambridge Commercial Historic District |
| Americus Hotel |
| Andalusia |
| Andrews Bridge Historic District |
| Anthracite Bank Building |
| Ayres, John, House |
| Bachman and Forry Tobacco Warehouse |
| Bair, Oliver, H., Funeral Home |
| Bath Crossroads Historic District |
| Bauern Freund Print Shop |
| Beallsville Historic District |
| Beaver Historic District |
| Bedford Historic District |
| Bellefonte Historic District |
| Bellevue Stratford Hotel |
| Benjamin Franklin Hotel |
| Berks County Trust Company |
| B.F. Good & Company Leaf Tobacco Warehouse |
| Biery's Port Historic District |
| Birchrunville General Store |
| Birchrunville Historic District |
| Bird-in-Hand Hotel |
| Bishop, John, House |
| Bloomsburg Historic District |
| Boalsburg Historic District |
| Bonnet's Tavern |
| Boston Store |
| Boyce Station |
| Bradford Downtown Historic District |
| Bridgewater Historic District |
| Brinton's Mill |
| Bristol Historic District |
| Broad Street Historic District |
| Broad Street Market |
| Brockerhoff Hotel |
| Brodbeck, S. B., Housing |
| Brookville Historic District |
| Brotherton Farm |
| Brownsburg Village Historic District |
| Brownsville Commercial Historic District |
| Brownsville Northside Historic District |
| Buhl Building |
| Bull, Thomas, House |
| Burnt Cabins Gristmill Property |
| Burnt Cabins Historic District |
| Butler County National Bank |
| Butler Historic District |
| Byrnes & Kiefer Building |
| Caldwell Tavern |
| Callowhill Industrial Historic District |
| Carlisle Historic District |
| Cashier's House |
| Center Bridge Historic District |
| Center City West Commercial Historic District |
| Centerville Historic District |
| Central Bethlehem Historic District |
| Central Hotel |
| Central Market |
| Central Norristown Historic District |
| Central Trust Company Buildings |
| Centre Furnace Mansion House |
| Chalybeate Springs Hotel |
| Chamberlin Iron Front Building |
| Charleroi Historic District |
| Charlestown Village Historic District |
| Chestnut Hill Historic District |
| Citizens National Bank of Latrobe |
| City Park Brewery |
| Clarkâs Ferry Tavern |
| Clarkson-Watson House |
| Coalport Historic District |
| Coatesville Historic District |
| Colley, Abel, Tavern |
| Colley, Peter, Tavern and Barn |
| Colonial Theatre |
| Columbia Historic District |
| Combination Baggage and Mail Car No. 5403 |
| Compass Inn |
| Concordville Historic District |
| Congregational Store |
| Consolidation Freight Locomotive No. 1187 |
| Consolidation Freight Locomotive No. 2846 |
| Consolidation Freight Locomotive No. 7688 |
| Coopersburg Historic District |
| Coudersport Historic District |
| Cumberland Valley Car |
| Dale, Samuel F., House |
| Danville Historic District |
| Davies House |
| DDI Electric Locomotive No. 36 |
| Delaware County National Bank |
| Dickson Tavern |
| Dickson Works |
| Dill's Tavern |
| Dilworthtown Historic District |
Data from United States Park Service and Wikidata