Ohio - Significance region: Local
| Shepard Street School |
| Sheridan House |
| Sherman, John, Memorial Gateway |
| Sherwood-Davidson And Buckingham Houses |
| Shield's Block |
| Shield's, Edwin M., House |
| Shier, Carl H., Barn |
| Shier, Carl H., Chicken House |
| Shier, Carl H., House |
| Shiloh Baptist Church |
| Shiloh Baptist Church |
| Shipherd, John J., House |
| Shore High School |
| Short North Historic District |
| Short Woods Park Mound |
| Shuey's Mill |
| Shuler & Benninghofen Woolen Mill |
| Shull-Lugenbuhl Farm |
| Sidaway Bridge |
| Sidney Courthouse Square Historic District |
| Sidney Walnut Avenue Historic District |
| Sigma Aplpha Epsilon Chapter House of Miami University |
| Sig's General Store |
| Silk City Diner #4655 |
| Simmons, Edwin H., House |
| Simpson, Walter, House |
| Simpson, William A., House |
| Sixth Street Historic District |
| Skeele, Capt. J. S., House |
| Skunk Hill Mounds |
| Skywood Farms |
| Slingluff, Dr. Joseph, House |
| Sloane, Rush R., House |
| Slocum Hall |
| Smart Building |
| Smead, David, House |
| Smead House |
| Smith, Benjamin, House |
| Smith, Charles William and Anna, House |
| Smith, David, House |
| Smith-Davis House |
| Smith, Edward, Jr., Farm |
| Smith, Edwin, House |
| Smith-Jessup House |
| Smith Road Bridge |
| Smith, Samuel, House And Tannery |
| Smith, William, House |
| Smith, William R., House |
| Smucker, J.M., House |
| Snead Mound |
| Snider, Dan F., Ford Dealership Building |
| Snow, John, House |
| Snow, Russ and Holland, Houses |
| Soldiers and Sailors Memorial Building and Madison Theater |
| Soldiers' and Sailors' Memorial Chapel |
| Soldiers and Sailors Monument |
| Soldiers Memorial Parkway and McKinley Memorial Parkway |
| Sollars Farmstead |
| Somerset Apartments, The |
| Sorrick-Oster Store |
| South Bass Island Light |
| South Brooklyn Commercial District |
| South Crescent Arms, The |
| Southern Ohio Lunatic Asylum |
| Southern Park Stable |
| South Fountain Avenue Historic District |
| South High Street Commercial Grouping |
| Southington Township School |
| South Leroy Meetinghouse |
| South Lincoln Avenue Historic District |
| South Main Street Historic District |
| South Park Historic District |
| South Park Site |
| South Ridge Schoolhouse |
| South Salem Academy |
| South Salem Covered Bridge |
| South Sandusky Avenue Historic District |
| South School |
| South South Street Historic District |
| South Ward District School |
| Southworth House |
| Spafford House |
| Spang, J., Baking Company |
| Speaker, Charles, House |
| Speedway Mound |
| Spencer's Landing |
| Spencer Town Hall |
| Spicer Manufacturing Building |
| Spitler, Samuel, House |
| Spitzer Building |
| Sprague-Deaver House |
| Sprague House |
| Sprague, Jonathan, House |
| Spread Eagle Tavern-Conrey, James D., House |
| Springboro Historic District |
| Springdale |
| Springfield Country Club |
| Springfield Downtown Historic District |
| Springfield Metallic Casket Company |
| Springfield Township School |
Data from United States Park Service and Wikidata
