North Carolina - Significance region: Local
| Narrows Dam and Power Plant Complex |
| Nash, Arthur C. and Mary S.A., House |
| Nashville Historic District |
| Navy Reserve Officers Training Corps (NROTC) Naval Armory at UNC-Chapel Hill |
| Nebel Knitting Mill, Former |
| Neill-Turner-Lester House |
| Neville, Jeter and Ethel, House |
| New Bern Municipal Building |
| New Hill Historic District |
| New Hope Presbyterian Church |
| New Hope Rural Historical Archeological District |
| Newland Road Site |
| Newsome, James, House |
| Newton Downtown Historic District |
| Newton Homesite and Cemetery |
| Nimocks House |
| Nissen Building |
| Nissen, S.J., Building |
| Nixon, Samuel, House |
| Norburn Terrace |
| Norfolk Southern Passenger Station |
| North Carolina Electrical Power Company Electric Generating Plant |
| North Charlotte Historic District |
| North Cherry Street Historic District |
| North Cherry Street Historic District |
| North Durham County Prison Camp (Former) |
| North Durham-Duke Park District |
| North Green Street-Bouchelle Street Historic District |
| North Long Street-Park Avenue Historic District |
| North Main Avenue Historic District |
| North Main Street Historic District |
| North Main Street Historic District |
| North Main Street Historic District |
| North Market Street Historic District |
| Northside Historic District |
| North Smithfield Historic District |
| North Third Avenue Historic District |
| North Washington Avenue Workers' House |
| Norwood Park Historic District |
| Nowell-Mayerburg-Oliver House |
| Oak City Christian Church |
| Oak Crest Historic District |
| Oakdale Cemetery |
| Oakdale Cotton Mill Village |
| Oakforest |
| Oak Grove Cemetery |
| Oak Grove School |
| Oaklana |
| Oak Lawn |
| Oakmont |
| Oak Plain Presbyterian Church |
| Oak View |
| Oakwood Historic District |
| Oakwood Historic District |
| Oakwood Historic District |
| Oaky Grove |
| Oates, John A., House |
| Oates, Livingston, Farm |
| Oberlin Cemetery |
| O'Brien, William Thomas, House |
| Occidental Life Insurance Company Building |
| Oconaluftee Archeological District |
| Oconaluftee Baptist Church |
| Odd Fellows Building |
| Odd Fellows Lodge |
| O'Hanlon Building |
| O'Kelly, Berry, Historic District |
| O'Kelly's Chapel |
| Old Bluff Presbyterian Church |
| Old Burying Ground |
| Old Fort Commercial Historic District |
| Old German Baptist Brethern Church |
| Old Richmond Schoolhouse and Gymnasium |
| Old South Mebane Historic District |
| Old Town Plantation |
| Old White Church Cemetery |
| Old Wilson Historic District |
| Oliver-Morton Farm |
| Oneida Cotton Mills and Scott-Mebane Manufacturing Company Complex |
| One Plaza Center |
| Opera House-Starnes Jewelers Building |
| Orange Street School |
| Orient Manufacturing Company-Chadwick-Hoskins No. 3 |
| Orr, Charles E., House |
| Ottari Sanitarium |
| Ottinger, Henry, House |
| Overcarsh House |
| Owen Family House and Cemetery |
| Owen-Harrison House |
| Oxford Historic District |
| Page, Williamson, House |
| Paisley-Rice Log House |
| Pantego Academy |
| Panther Branch School |
| Parham, Maria, Hospital |
| Parker, Francis, House |
| Parker, James H., House |
| Parker, King, House |
| Parks-Cramer Company Complex, Former |
| Paschal House |
Data from United States Park Service and Wikidata
