Michigan - Significance region: Local
| Rood Building |
| Rosedale Gardens Historic District |
| Rosedale Park Historic District |
| Rose Place Historic District |
| Ross, David M., House |
| Round Island Passage Light |
| Rowe House |
| Royal Palm Hotel |
| Royce, Steven, House |
| Russell, William, House |
| Sackett, Russell, House |
| Sacred Heart-Gros Cap Church |
| Sacred Heart Roman Catholic Church, Convent and Rectory |
| Sage Library |
| Saginaw Armory |
| Saginaw Central City Expansion District |
| Saginaw Central City Historic Residential District |
| Saginaw City Historic Business District |
| Saginaw County Fairgrounds Main Gate |
| Saginaw News Building |
| Saint Andrew's Memorial Episcopal Church |
| Saint Elizabeth's Church |
| Saint Henry's Evangelical Lutheran Church and Cemetery |
| Saint Ignatius Church and Cemetery |
| Saint Ignatius Loyola Church |
| Saint James' Episcopal Church |
| Saint Joseph's Catholic Church |
| Saint Joseph Seminary |
| Saint Louis Downtown Historic District |
| Saint Mary of Redford Catholic Church |
| Saint Mary's School |
| Saint Matthew Parish |
| Saint Michael and All Angels' Episcopal Church and Cambridge Township Cemetery |
| Saint Paul Catholic Church Complex |
| Saint Paul Manor Apartments |
| Saint Rita Apartments |
| Saints Peter And Paul Church |
| Saline First Presbyterian Church |
| Sandenburgh-Rogers Summer Resort Complex |
| Sand Hills Light Station |
| Sashabaw Presbyterian Church |
| Saugatuck Pump House |
| Sault Ste. Marie Historic Commercial District |
| Savings Bank Building |
| Scalcucci's Grocery |
| Scarab Club |
| Schantz, George, House and Store |
| Schapler, Frank, House |
| Scottville School |
| Second Arenac County Courthouse |
| Second Street Bridge |
| Second Street-Gun River Bridge |
| Sessions Schoolhouse |
| Seventh Day Adventist Church |
| Seventh Street-Black River Bridge |
| Sexton, William K. and Nellie, House |
| Shafer's Grocery and Residence |
| Shaffer, Enoch, House |
| Sharp, Ella, House |
| Shelden Avenue Historic District |
| Shelden-Dee Block |
| Shelden, Ransom B., House |
| Sheldon Inn |
| Sherman City Union Church |
| Sherwood, James Noble, House |
| Shiawassee County Courthouse |
| Shields, Patrick and Sarah Dobbins, House |
| Shrine of the Black Madonna of the Pan African Orthodox Christian Church |
| Shriner-Ketcham House |
| Sibley, Frederic M., Lumber Company Office Building |
| Siebold Farm/Ruehle (Realy) Farm |
| Silliman, Arthur, House |
| Sisters of the Order of Saint Dominic Motherhouse Complex |
| Sleeping Bear Inn |
| Sligh Furniture Company Building |
| Smith-Culhane House |
| Smith-Dengler House |
| Smith, George and Mary Pine, House |
| Smith House |
| Smith, LeRoy, House |
| Smith, Samuel L., House |
| Smith's Chapel |
| Smith-Turner House |
| Soderman, John, Farmhouse |
| Somerset Apartments |
| Somerville Barn |
| South Berrien Center Union Church and Cemetery |
| South Fox Island Light Station |
| South Jefferson Avenue Historic District |
| South Manitou Island Lighthouse Complex and Life Saving Station Historical District |
| South Michigan Avenue Historic District |
| South Monroe Street Historic District |
| South Pointe Drive-Frenchman's Creek Bridge |
| South Range Community Building |
| South Union Street-Boardman River Bridge |
| Sparks-Anderson House |
| Sparks, G. P., House |
| Spectacle Reef Light Station |
| Spies Boardinghouse |
| Sprague, Rollin, Building-Old Stone Store |
Data from United States Park Service and Wikidata
