Massachusetts - Area of significance: Architecture
| South Hingham Historic District |
| South Junior High School |
| South Lee Historic District |
| South Main Street School |
| South Middleborough Historic District |
| South Reading Academy |
| South School |
| South School |
| South Station Headhouse |
| South Street Historic District |
| South Swansea Union Church |
| South Union School |
| South Unitarian |
| South Washington Street Historic District |
| Southwick-Daniels Farm |
| Southwick, Elisha, House |
| Southwick House |
| Southwick, Israel, House |
| South Worcester Branch Library |
| South Worthington Historic District |
| South Yarmouth/Bass River Historic District |
| Sparrow, Richard, House |
| Spaulding Block |
| Spaulding, Zeb, House |
| Spear, Seth, Homestead |
| Spencer-Pierce-Little House |
| Spencer Town Center Historic District |
| Spicket Falls Historic District |
| Spofford-Barnes House |
| Sprague House |
| Springfield Armory |
| Springfield District Court |
| Springfield Fire & Marine Insurance Co. |
| Springfield Safe Deposit and Trust Company |
| Springfield Steam Power Company Block |
| Springfield Street Historic District |
| Spring Hill Historic District |
| Spring Hill Historic District |
| Springside Park |
| Spurr, Eliphalet, House |
| Spurr, John, House |
| Stacy Building |
| Stacy, George O., House |
| Stafford Mills |
| Standish, James H., House |
| Stanley, Leonard W., House |
| St. Anne's Church and Parish Complex |
| Stanstead, The |
| Stanton, Jacob, House |
| Staples, Sylvanus N., House |
| Stark Building |
| Stark, Edward, House |
| Stark, Robert M., House |
| State Armory |
| State Lunatic Hospital at Danvers |
| State Normal Training School |
| St. Charles Borromeo Church |
| Stearns, Amos, House |
| Stearns Building |
| Stearns, R. H., House |
| Sterling Center Historic District |
| Sterling, Ella Mahalla Cutter, House |
| Stetson-Ford House |
| Stetson Hall |
| Stetson House |
| Stevens, Abiel, House |
| Stevens' Building |
| Stevens, Daniel, House |
| Stevens Linen Works Historic District |
| Stewart, Frank H., House |
| Stewart, Henry, House |
| St. George Antiochian Orthodox Church |
| St. George's Greek Orthodox Church |
| Stickney-Shepard House |
| Still River Baptist Church |
| Stimpson, William, House |
| St. James Apartments, The |
| St. James Episcopal Church |
| St. John`s Catholic Church |
| St John's Congregational Church & Parsonage-Parish for Working Girls |
| St. John's Roman Catholic Church |
| St. Joseph's Church |
| St. Joseph's Church |
| St. Joseph's Convent and School |
| St. Joseph's Orphanage |
| St. Joseph's Roman Catholic Church Complex |
| St. Joseph's School |
| St. Joseph's School |
| St. Louis Church |
| St. Luke's and St. Margaret's Church |
| St. Luke's Episcopal Church |
| St. Marks |
| St. Mark's Methodist Church |
| St. Mary's Cathedral and Rectory |
| St. Mary's Catholic Church |
| St. Mary's Church and Cemetery |
| St. Mary's Complex |
| St. Mary's Episcopal Church |
| St. Mary's Roman Catholic Church Complex |
| St. Matthews |
Data from United States Park Service and Wikidata
