Massachusetts - Area of significance: Architecture
| St. Michael's Church |
| St. Nicholas Orthodox Church and Rectory |
| Stockbridge Casino |
| Stoliker, Edna, Three-Decker |
| Stone Building |
| Stone, Edward, Three-Decker |
| Stoneham Firestation |
| Stoneham Public Library |
| Stoneholm |
| Stone House |
| Stone, Joseph, House |
| Stone, Joseph L., House |
| Stone, Lorenzo R., House |
| Stony Brook-Factory Village Historic District |
| Stony Farm |
| Story Grammar School |
| Stoughton, Mary Fisk, House |
| Stoughton Railroad Station |
| St. Patrick's Church |
| St. Patrick's Church |
| St. Paul's Church |
| St. Paul's Parish Church |
| St. Peters Catholic Church |
| St. Peter's Roman Catholic Church-St. Mary's School |
| Straightsmouth Island Light |
| Strathmore Road Historic District |
| Stratton, Edward B., House |
| Strong House |
| Strong's Block |
| St. Stephen's Church |
| St. Stephen's Memorial Church |
| St. Thomas Epsicopal Church |
| Students House |
| Sturbridge Common Historic District |
| Sturtevant, Leonard, House |
| Sudbury Aqueduct Linear District |
| Sudbury Center Historic District |
| Sudbury Dam Historic District |
| Suffolk County Jail |
| Sullivan, Edward, House |
| Sullivan's Corner Historic District |
| Summer Street Historic District |
| Sumner and Gibbs Streets Historic District |
| Sumner, George, House |
| Sumner Hill Historic District |
| Sunderland Center Historic District |
| Superior Courthouse and Bartlett Mall |
| Sutton Block |
| Sutton Center Historic District |
| Swadkins, Thomas, House |
| Swampscott Fish House |
| Swampscott Railroad Depot |
| Swan, Asie, House |
| Swan, Henry, House |
| Swansea Friends Meetinghouse and Cemetery |
| Swansea Village Historic District |
| Swasey, James, House |
| Sweet, Albert, House |
| Sweetser, Daniel, House |
| Sweetser, Michael, House |
| Sweetser, Warren, House |
| Swetland-Pease House |
| Swift, D. Wheeler, House |
| Sykes House |
| Symmes, Deacon John, House |
| Symmes, Marshall, House |
| Symmes, Stephen, Jr., House |
| Symonds, Thomas, House |
| Symphony and Horticultural Halls |
| Symphony Hall |
| Taconic and West Avenues Historic District |
| Taft, Aaron, House |
| Taft, Bazaleel, Jr., House and Law Office |
| Taft Brothers Block |
| Taft, George, House |
| Taft, Hon. Bazaleel, House |
| Taft, Moses, House |
| Taft, Samuel, House |
| Taft, Zadock, House |
| Tapin, Eugene, House |
| Tapley Building |
| Tarklin School |
| Tarpaulin Cove Light |
| Tashmoo Springs Pumping Station |
| Taunton Alms House |
| Taunton Green Historic District |
| Taunton Public Library |
| Taunton State Hospital |
| Tavern Acres Historic District |
| Tavern Farm, Old |
| Tay, Jesse, House |
| Taylor-Bray Farm |
| Taylor Square Firehouse |
| Teaticket School |
| Ted's Diner |
| Temple Building |
| Temple, Joseph, House |
| Temple, Mark, House |
| Temple Place Historic District |
| Templeton Common Historic District |
Data from United States Park Service and Wikidata