Kentucky - Area of significance: Architecture
| Salem Baptist Church |
| Salem Methodist Episcopal Church and Parsonage |
| Sale, Reuben, House |
| Salter, Tom, House |
| Salyer, Addison, House |
| Salyer House |
| Samuels, T. W., Distillery Historic District |
| Sanders, Durham, House |
| Sanders, Robert, House |
| Sandidge House |
| Sandusky House |
| Sandy Bluff |
| Satterfield, Edward and Julia, House |
| Sauer, August, House |
| Saunders-Boyd House |
| Sauser Farm |
| Savageot, Jacob, House and Saloon |
| Savoy Historic District |
| Sawyer, David, House |
| Sayre Female Institute |
| Scearce House |
| Scearce-Roush House |
| Schneikert, Valentine, House |
| Schuster Building |
| Schwert, Drs. George W. & Margaret, House |
| Scobee, Robert, House |
| Scotland |
| Scott and Wilson Houses District |
| Scott Avenue Historic District |
| Scott County Courthouse |
| Scott County Jail Complex |
| Scott, Dill, House |
| Scott House |
| Scott, John Harvey, House |
| Seaman Sisters' House |
| Sears, Roebuck and Company Store |
| Sebastian Log House |
| Seclusaval |
| Second and Market Streets Historic District |
| Second Presbyterian Church |
| Seelbach Hotel |
| Seeley, Edward B., House |
| Selema Hall |
| Seminary Square Historic District |
| Settle, E. E., House |
| Settle, Franklin, House |
| Seventh Street Historic District |
| Seventh Street School |
| Shady Brook Farm |
| Shady Grove |
| Shady Rest |
| Shady Side |
| Shakertown at Pleasant Hill Historic District |
| Shaker West Lot Farm |
| Shallcross |
| Shanklin House |
| Sharp House |
| Shawhan, Joseph, House |
| Shawnee Elementary School |
| Shawnee High School |
| Shawnee Springs |
| Shearer Store |
| Sheehan House |
| Shelburne-Cox House |
| Shelby Academy |
| Shelby County Courthouse and Main Street Commercial District |
| Shelby Family Houses |
| Shelby Park Branch Library |
| Shelbyville L & N Railroad Depot |
| Shell, John, Cabin |
| Sherley Mansion |
| Sherman Tavern |
| Shipp House |
| Shipp, Laban, House |
| Shobe, Moses, House |
| Short, George, House |
| Showalter House |
| Shropshire House |
| Shryack, Frederick, House |
| Shwab House |
| Simeon Lewis Rural Historic District |
| Simmons House |
| Simms-Edelen House |
| Simms-Mattingly House |
| Simmstown |
| Simpson County Courthouse |
| Simpson Log House |
| Simpsonville Christian Church |
| Simpsonville Methodist Church |
| Simrall-Warfield House |
| Sisters of Charity of Nazareth Historic District |
| Site Bn-54 |
| Skees, Richard, House |
| Skees, William, House |
| Skillman House |
| Slaton, James E., House |
| Sleadd, William, Farm |
| Sloss, John, House |
| Smith, Beecher, House |
| Smith, David H., House |
Data from United States Park Service and Wikidata
