Florida - Criteria: C (architecture/engineering)
| Sanderling Beach Club |
| Sand Key Lighthouse |
| SAN FELIPE Shipwreck Site |
| Sanford Commercial District |
| Sanford Grammar School |
| Sanford Residential Historic District |
| San Jose Administration Building |
| San Jose Country Club |
| San Jose Estates Gatehouse |
| San Juan De Aspalaga Site |
| San Pedro y San Pablo de Patale |
| Santa Rosa Hotel |
| Sapp House |
| Sarasota County Courthouse |
| Sarasota Herald Building |
| Sarasota Times Building |
| Sarasota Woman's Club |
| Saxon, Frank, House |
| Schmidt-Godert Farm |
| Schueler, George, House |
| Scott Commercial Building |
| Seaboard Air Line Depot, Old-Sebring |
| Seaboard Air Line Dining Car-#6113 |
| Seaboard Air Line Lounge Car-6603 |
| Seaboard Airline Railroad Station |
| Seaboard Air Line Railway Station, Old |
| Seaboard Coast Line Railroad Depot |
| Seaboard Coastline Railroad Passenger Station |
| Seabreeze Historic District |
| Seagate |
| Sears, Roebuck and Company Department Store |
| Sebastian Grammar and Junior High School |
| Sebring Downtown Historic District |
| Sebring, H. Orvel, House |
| Security Building |
| Seminole Cafe and Hotel |
| Seminole County Home |
| Seminole Heights Residential District |
| Seminole Inn |
| Seybold Baking Company Factory |
| Shady Grove Primitive Baptist Church |
| Shelfer, E. B., House |
| Sherman Arcade |
| Shoreland Arcade |
| Sikes House |
| Singleton, Micajah T., House |
| Smith, Dr. Chandler Holmes, House |
| Smith, E. C., House |
| Smith, H. W., Building |
| Smoky Hollow Historic District |
| Sneads Community House and Old Pump |
| Snell Arcade |
| Snyder Memorial Methodist Episcopal Church |
| Solla-Carcaba Cigar Factory |
| Sollner-Wall House |
| Sombrero Key Light |
| Sopchoppy High School Gymnasium, Old |
| Sopchoppy School |
| Souder, Paul M., House |
| South Bartow Residential District |
| South Beach Street Historic District |
| South Brooksville Avenue Historic District |
| Southeast Gainesville Residential District |
| South Jacksonville Grammar School |
| South Lake Morton Historic District |
| South Ridgewood Elementary School |
| South River Drive Historic District |
| Southside School |
| South Side School |
| South Ward School |
| Southwick-Harmon House |
| Spanish Apartments |
| Spanish Coquina Quarries |
| Spell House |
| Springfield Historic District |
| Spring Lake Community Center |
| SS AMERICAN VICTORY (Victory ship) |
| SS COPENHAGEN (shipwreck) |
| S & S Sandwich Shop |
| St. Anastasia Catholic School, Old |
| Stanbury Cottage |
| Standard Oil Service Station |
| St. Andrew School |
| St. Andrew's Episcopal Church |
| St. Andrews Episcopal Church |
| St. Anthony School |
| Stanton, Edwin M., School |
| St. Augustine Civic Center |
| St. Augustine Lighthouse and Keeper's Quarters |
| St. Augustine Town Plan Historic District |
| St. Augustine Water Works |
| Stephens House |
| Stetson, John B., House |
| Stetson University Campus Historic District |
| Stevens, Ann, House |
| St. Gabriel's Episcopal Church |
| St. George Episcopal Church |
| St. James A. M. E. Church |
| St. James Building |
| St. John's Baptist Church |
Data from United States Park Service and Wikidata
