Colorado - Area of significance: Commerce
| American National Bank Building |
| Anderson, Peter, House |
| Animas Forks |
| Antlers Cafe and Bar |
| Argo Tunnel and Mill |
| Arvada Downtown |
| Astor House Hotel |
| Austin Building |
| Bailey House |
| Baldpate Inn |
| Barker House |
| Bats Grocery Store |
| Baur Confectionery Company |
| Baxter House |
| Beaumont Hotel |
| Bell and Canant Mercantile-Crossan's M and A Market |
| Bell Mercantile |
| Bent's Old Fort National Historic Site |
| Bimson Blacksmith Shop |
| Blue Jay Inn |
| Bode-Stewart House |
| Boggsville |
| Boston Building |
| Bouvier-Lothrop House |
| Breckenridge Historic District |
| Brown, J. S., Mercantile Building |
| Brueger Brothers Building and Annex |
| Building at 1389 Stuart Street |
| Building at 1390 Stuart Street |
| Building at 1435 Stuart Street |
| Building at 1444 Stuart Street |
| Building at 1471 Stuart Street |
| Burlington Hotel |
| Butters, Alfred, House |
| Callahan, T. M., House |
| Canon City Downtown Historic District |
| Central City-Black Hawk Historic District |
| Chamber of Commerce Building |
| Citizens National Bank Building |
| Cliff House |
| Colorado and Southern Railway Depot |
| Colorado Building |
| Colorado National Bank Building |
| Commercial Hotel |
| Como Roundhouse, Railroad Depot and Hotel Complex |
| Corazon de Trinidad |
| Curtis Hardware Store |
| Davies' Chuck Wagon Diner |
| Denver and Rio Grande Western Railroad Locomotive No. 315 |
| Denver, Boulder and Western Railway Historic District |
| Denver City Railway Company Building |
| Denver Dry Goods Company Building |
| Denver & Rio Grande Railroad San Juan Extension |
| Dey Building |
| Downtown Boulder Historic District |
| Downtown Florence Historic District |
| Downtown Longmont Historic District |
| Downtown Loveland Historic District |
| Downtown Sterling Historic District |
| Doyle Settlement |
| Duke, Nathaniel W., House |
| Durango-Silverton Narrow-Gauge Railroad |
| Eastholme |
| Eastlake Farmers Co-Operative Elevator Company |
| Eaton, Aaron James, House |
| Edgerton House |
| Eleventh Avenue Hotel |
| El Pueblo |
| Englewood I.O.O.F. Lodge No. 138 Building |
| Enterprise Hill Historic District |
| Equitable Building |
| Estabrook Historic District |
| Exon & Rush Meat Market and Mercantile |
| Fairplay Hotel |
| Farmers State Bank of Cope |
| First Avenue Hotel |
| First National Bank Building |
| First National Bank Building |
| First National Bank Building |
| Fisher, William G., House |
| Fitch Terrace |
| Flower, John S., House |
| Fort Vasquez |
| Foster, A. C., Building |
| Fountain Inn |
| Frazier, R. T., House |
| Gates, Russell and Elinor, Mansion |
| Giddings Building |
| Glenisle |
| Golden Burro Cafe and Lounge |
| Gold Miner Hotel |
| Greeley Downtown |
| Greeley, Salt Lake and Pacific Railroad-Stout Branch |
| Green Mercantile Store |
| Guerrieri-Decunto House |
| Hart, Wilson A., House |
| Hayden Co-Operative Elevator Company |
| Hayden Rooming House |
| Hazelhurst |
| Hendrie and Bolthoff Warehouse Building |
Data from United States Park Service and Wikidata
