Puerto Rico - Area of significance: Architecture
| Plaza del Mercado de Manati |
| Polvorin de Miraflores |
| Pomar, Pico, Residence |
| Ponce High School |
| Ponce Public School 1913 |
| Primera Iglesia Bautista de Caguas |
| Public Health Unit at Yauco |
| Puerta de Tierra Historic District-Distrito Histórico de Puerta de Tierra |
| Puerto Rico Ilustrado-Edificio El Mundo |
| Puerto Rico Island Penitentiary |
| Quinta Vendrell |
| Rafael Cordero Graded School |
| Rafael M. Labra High School |
| Ramirez, Dona Antonia, Residencia |
| Residence Lopez |
| Residencia Aboy-Lompre |
| Residencia de Senoritas Universidad de Puerto Rico; Rio Piedras |
| Residencia Don Andres Hernandez |
| Residencia Gonzalez Vivaldi |
| Residencia Heygler |
| Residencia Machin-Ramos |
| Residencia Ramirez De Arellano en Guanajibo |
| Rivera, Luis Munoz, School |
| Rivera, Nazario, Residencia |
| Rodriguez Morales, Juana, House |
| Rosaly-Batiz House |
| Rum Pilot Plant |
| Saez, Antonia, School |
| Salazar-Candal House |
| Sanctuary of Blessed Martin de Porres |
| San German Historic District |
| San Juan National Historic Site |
| Santa Elena Hacienda |
| Santuario de la Monserate de Hormigueros and Casa de Peregrinos |
| School of Tropical Medicine |
| Semidey, Maria Davila, School |
| Sepulveda, Berta, House |
| Smaine-Ortiz House |
| SS ANTONIO LOPEZ Shipwreck Site and Remains |
| Subira House |
| Superintendent of Lighthouses' Dwelling |
| Supreme Court Building |
| Teatro Ideal |
| Teatro Liberty |
| Teatro Yaguez |
| Toro, Fernando Luis, Casa |
| University of Puerto Rico Tower and Quadrangle |
| US Custom House |
| US Custom House |
| US Custom House |
| US Custom House |
| US Post Office and Courthouse |
| US Post Office and Courthouse |
| Vieques Pharmacy |
| Villa Del Mar |
| Villa Julita |
| Villaronga House |
| Webster, Daniel, School |
| Williams Products Corporation |
Data from United States Park Service and Wikidata