West Virginia - Area of significance: Commerce
| Lockwood Historic District |
| Loewenstein and Sons Hardware Building |
| Lost River General Store |
| Lowther Store |
| Madison National Bank |
| Malden Historic District |
| Mannington Historic District |
| Mason-Drennen House |
| Masonic Temple-Watts, Ritter, Wholesale Drygoods Company Building |
| Matewan Historic District |
| McGrew, James Clark, House |
| McNeel Mill |
| Meadow River Lumber Building |
| Mercer Street Historic District |
| Miller, Joseph S., House |
| Miller Tavern and Farm |
| Mohler, William E., House |
| Mollohan Mill |
| Morgantown Green Book Historic District |
| Morgantown Wharf and Warehouse Historic District |
| Moundsville Commercial Historic District |
| Mountaineer Hotel |
| Mount Hope Historic District |
| Mud River Covered Bridge |
| Mullens Historic District |
| Neale, George, Jr., House |
| New Martinsville Downtown Historic District |
| New River Company General Office Building |
| Nicholas County Bank |
| Nixon, Senator P. E., House |
| North, John A., House |
| North River Mills Historic District |
| North Street Historic District |
| North Wheeling Historic District |
| Page Coal and Coke Company Store |
| Peerless Coal Company Store |
| People's Bank |
| Perly, Fred A., House |
| Philippi B & O Railroad Station |
| Phillips-Sprague Mine |
| Pocahontas County Courthouse and Jail |
| Pocahontas Fuel Company Store |
| Pocahontas Fuel Company Store |
| Pocahontas Fuel Company Store and Office Buildings |
| Post, William, Mansion |
| Price, R. T., House |
| Prince Brothers General Store-Berry Store |
| Quality Hill Historic District |
| Ramsdell, Z. D., House |
| "Ravenswood ""Old Town"" Historic District" |
| Red Horse Tavern |
| Reed's Mill |
| Ripley Historic District |
| Ruddell General Store |
| Shinnston Historic District |
| Sistersville Historic District |
| Smith, W.H., Hardware Company Building |
| Snyder, Noah, Farm |
| Sophia Historic District |
| South Bluefield Historic District |
| South Water Street Historic District |
| St. Albans Main Street Historic District |
| Stark, Henry and Julia Hoard, House |
| Sterrett Brothers' Dry Goods Store |
| Sutton Downtown Historic District |
| Tarr, Peter, Furnace Site |
| Terra Alta Bank |
| Thomas Commercial Historic District |
| Thornburg House |
| Thurmond Historic District |
| Town of Bath Historic District |
| Travelers Rest |
| Tucker County Bank Building |
| Tuckwiller Tavern |
| Tyree Stone Tavern |
| Union Historic District |
| United Carbon Building |
| Upper Oakhurst Historic District |
| U.S. Coal and Coke Company |
| Vandiver-Trout-Clause House |
| VanDoren, Jacob, House |
| Van Metre Ford Stone Bridge |
| Walnut Grove |
| Warfield-Dye Residence |
| Warwood Historic District |
| Welch Commercial Historic District |
| Wellsburg Historic District |
| Wellsburg Wharf |
| Wells Inn |
| Weston Downtown Historic District |
| West Union Downtown Historic District |
| Wheeling Historic District |
| Wheeling Warehouse Historic District |
| Whipple Company Store |
| Woodrums' Building |
Data from United States Park Service and Wikidata
