Virginia - Significance region: National
| Ripshin |
| Rising Sun Tavern |
| Rosewell |
| Rotunda, University of Virginia |
| Ruffin, Edmund, Plantation |
| Sabine Hall |
| Saltville Battlefields Historic District |
| Saratoga |
| SAVANNAH (nuclear ship) |
| Sayler's Creek Battlefield |
| Scotchtown |
| Semple, James, House |
| Seven Pines National Cemetery |
| Shack Mountain |
| Shirley |
| Shockoe Hill Burying Ground Historic District |
| Shockoe Hill Cemetery |
| Signal Hill |
| Skyline Drive Historic District |
| Smith's Fort |
| Southern Albemarle Rural Historic District |
| Southwest No. 1 Boundary Marker of the Original District of Columbia |
| Southwest No. 2 Boundary Marker of the Original District of Columbia |
| Southwest No. 3 Boundary Marker of the Original District of Columbia |
| Southwest No. 4 Boundary Marker of the Original District of Columbia |
| Southwest No. 5 Boundary Marker of the Original District of Columbia |
| Southwest No. 6 Boundary Marker of the Original District of Columbia |
| Southwest No. 7 Boundary Marker of the Original District of Columbia |
| Southwest No. 8 Boundary Marker of the Original District of Columbia |
| Southwest Virginia Museum Historical State Park |
| Spence's Point |
| Stabler-Leadbeater Apothecary Shop |
| Staunton Hill |
| Staunton National Cemetery |
| St. James Church |
| St. John's Church |
| St. John's Church Historic District |
| St. John's Episcopal Church |
| St. Luke Building |
| St. Luke's Church |
| St. Paul's Church |
| St. Peter's Church |
| Stratford Hall |
| Stuart, J.E.B., Birthplace |
| Thoroughfare Gap Battlefield |
| Thoroughgood House |
| Thunderbird Archeological District |
| Town of Barton Heights Historic District |
| Tredegar Iron Works |
| Tuckahoe |
| Tyler, John, House |
| Unison Battlefield Historic District |
| United Daughters of the Confederacy Memorial Building |
| University Of Virginia Historic District |
| U.S. Customhouse |
| USS WISCONSIN (BB-64) battleship |
| Valentine Museum |
| Variable Density Tunnel |
| Vint Hill Farms Station Historic District |
| Virginia Military Institute Historic District |
| Virginia School for the Deaf and Blind |
| Virginia State Capitol |
| Virginia Washington Monument |
| Washington and Lee University Historic District |
| Washington, George, Boyhood Home Site |
| Washington National Airport Terminal and South Hangar Line |
| Washington's, George, Distillery and Gristmill |
| Waterford Historic District |
| Waveland |
| Werowocomoco Archeological Site |
| West Cornerstone |
| Western State Hospital Complex |
| Westover |
| Weyanoke |
| White House of the Confederacy |
| Williamsburg Historic District |
| Williamson Site |
| Wilson, Woodrow, Birthplace |
| Winchester National Cemetery |
| Winona |
| Woodlawn Plantation |
| Wren Building, College of William and Mary |
| Wythe House |
| Yeocomico Church |
Data from United States Park Service and Wikidata
