Texas - Significance region: Local
| Saathoff House |
| Sacred Heart Catholic Church |
| Sacred Heart Conventual Chapel |
| Sadler Site |
| Saenger Theater |
| Saffold Dam |
| Saigling House |
| Saint Andrew's Episcopal Church |
| Saint Anthony Hotel |
| Saint Anthony's Catholic Church |
| Saint James Second Street Baptist Church |
| Saint John's Methodist Church |
| Saint Joseph's Chapel |
| Saint Paul's Episcopal Church |
| Sam Houston Hotel |
| Sampson, George W., House |
| San Angelo National Bank Building |
| San Angelo National Bank, Johnson and Taylor, and Schwartz and Raas Buildings |
| San Angelo Telephone Company Building |
| San Antonio City Cemeteries Historic District, Old |
| San Antonio River Valley (West of Goliad) Rural Historic District |
| San Antonio US Post Office and Courthouse |
| San Antonio Water Works Pump Station No. 2 |
| San Augustine Commercial Historic District |
| San Augustine County Courthouse and Jail |
| Sanborn, Henry B. and Ellen M., House |
| Sanders House |
| Sanderson, James S., House |
| Sanders, William Edward, House |
| San Elizario Historic District |
| San Francisco Ranch |
| Sanger Brothers Building |
| Sanger Brothers Building (1925) |
| Sanger Brothers Complex |
| Sanguinet, Marshall R., House |
| San Jacinto County Courthouse |
| San Jacinto County Jail |
| San Jacinto Senior High School |
| San Jacinto Warehouse |
| San Marcos Colored School Home Economics Building |
| San Marcos Milling Company |
| San Marcos Telephone Company |
| San Saba County Courthouse |
| Sansom-Schmalenbeck House |
| Santa Fe Building |
| Santa Fe-Frisco Depot |
| Santa Fe Passenger Depot |
| Santa Fe Railroad Station |
| Santa Fe Railway Company Freight Depot |
| Santa Fe Railway Freight Depot |
| Santa Fe Terminal Building No. 4 |
| Santa Fe Terminal Buildings No.1 and No. 2 |
| Sausley House |
| Saxon Motor Car Store |
| Sayers, Gov. Joseph, House |
| Sayles Boulevard Historic District |
| Sayles, Henry, House |
| Schaeffer, W. F., House |
| Schemedes, Kurt and Meta, House |
| Schlenker, Almot, House |
| Schlenker-Kolwes House |
| Schlesser-Burrows House |
| Schlumberger Well Surveying Corporation Building |
| Schmidt House |
| Schneemann, William, House |
| Schneider Hotel |
| Schneider, J. P., Store |
| Schreiner, Capt. Charles, Mansion |
| Schroeder, Fritz Paul and Emma, House |
| Schroeder-Yturri House |
| Schuerenberg, F. W., House |
| Schuerenberg, R. A., House |
| Schulze, Walter, House and Industrial Structure |
| Scott, A. M., House |
| Scottish Rite Cathedral |
| Scottish Rite Dormitory |
| Scott, L. A., House |
| Scott-Majors House |
| Scott, Zachary T. and Sallie Lee, Sr. House |
| Seaholm Power Plant |
| Seale, Wynn, Junior High School |
| Sealy, J.L., Building |
| Sears, Rev. Henry M. and Jennie, House |
| Sears, Roebuck and Company Warehouse and Service Center |
| Sebastopol |
| Second Trinity University Campus |
| Sedberry House |
| Seelhorst, W. E., House |
| Seguin Commercial Historic District |
| Selma Stagecoach Stop and Post Office |
| Sengelmann Hall and City Meat Market Building |
| Sessums-James House |
| Settles Hotel |
| Seward Plantation |
| Shackelford County Courthouse Historic District |
| Shadow Lawn Historic District |
| Shannon's Funeral Home |
| Shapira Hotel |
| Sharp House |
| Sharrock, Everard Jr., Farmstead |
Data from United States Park Service and Wikidata
