Tennessee - Area of significance: Architecture
| RyeMabee |
| Rymer, Bradford, Barn |
| Sabine Hill |
| Sacred Heart of Jesus Church |
| Sacred Heart of Jesus Church |
| Saint Margaret Mary Catholic Mission |
| Saints Peter and Paul Catholic Church and Buildings |
| Salem Presbyterian Church |
| Sam Davis Avenue Historic District |
| Savage House |
| Savannah Historic District |
| Scales, Absalom, House |
| Scales, James, House |
| Scarritt College Historic District |
| Schwartz, Robert, and Company Building |
| Scimitar Building |
| Scott, Andrew, House |
| Scott Mansion |
| Searcy-Matthews-Tarpley Farm |
| Sears, Roebuck and Company Catalog Distribution Center and Retail Store |
| Seay, William Washington, House |
| Second Avenue Commercial District |
| Second Congregational Church |
| Second Presbyterian Church |
| Senter-Rooks House |
| Settlement School Community Outreach Historic District |
| Settlement School Dormitories and Dwellings Historic District |
| Seven Islands Methodist Church |
| Sevier County Courthouse |
| Sevierville Commercial Historic District |
| Sewanee Fire Lookout Tower |
| Seward, John, House |
| Shackle Island Historic District |
| Shadowlawn Historic District |
| Sharp, Elisha, House |
| Shavin, Seamour and Gerte, House |
| Shaw, Abner T., House |
| Shea, John F., House |
| Shelbridge |
| Shelbyville Courthouse Square Historic District |
| Shelbyville Railroad Station |
| Shields' Station |
| Shiflett, G. W., Barn |
| Shiloh Baptist Church |
| Shiloh National Military Park |
| Shofners' Lutheran Church and Cemetery |
| Shook, Col. A. M., House |
| Shook-Vanzant Farm |
| Shrine Building |
| Shults Grove Methodist Church |
| Shute, Thomas, House |
| Signal Knitting Mills |
| Signal Mountain Elementary School |
| Signal Mountain Historic District |
| Simerly-Butler House |
| Simmons, Peter, House |
| Sims, Capt. William, House |
| Sims, John Green, House |
| Skipwith Hall |
| Smith, Alexander, House |
| Smith-Carter House |
| Smith, Christopher H., House |
| Smith County Courthouse |
| Smith, Dr. Benjamin Franklin, House |
| Smith Farmhouse |
| Smith-Hoffman House |
| Smith-Little-Mars House |
| Smith, Robert Andrew, Farm |
| Smith, Robert H., Law Office |
| Smithson, Nathaniel, House |
| Smith, Warner Price Mumford, House |
| Smotherman House |
| Sneed, Constantine, House |
| Soldiers and Sailors Memorial Auditorium |
| Somerville Historic District |
| South Bluffs Warehouse Historic District |
| South College Street Historic District |
| South Elk Street Historic District |
| Southern Methodist Publishing House |
| Southern Railway Freight Depot |
| Southern Terminal and Warehouse Historic District |
| South Holston Hydroelectric Project |
| South Main Street Historic District |
| South Main Street Historic District |
| South Main Street Historic District |
| South Market Historic District |
| South Parkway-Heiskell Farm Historic District |
| South Pittsburg Historic District |
| South Pulaski Historic District |
| Southwestern at Memphis Historic District |
| Southwestern at Memphis Sorority Row Historic District |
| Sparkman-Skelley Farm |
| Sparta Nashville, Chattanooga and St. Louis Railroad Depot |
| Sparta Residential Historic District |
| Sparta Rock House |
| Speedway Terrace Historic District |
| Sperry-Smith House |
| Spring Creek Presbyterian Church |
| Springfield Town Square Historic District |
| Spring Hill Presbyterian Church |
Data from United States Park Service and Wikidata
