South Dakota - Significance region: Local
| Volga Hospital |
| Von Woehrmann Building |
| Vostad Farm |
| Waddell Block |
| Waddel Mansion |
| Wagner House |
| Wagner, Joseph V., House |
| Wakonda State Bank |
| Waldorf Hotel |
| Walla Lutheran Church |
| Walsh Barn |
| Walters, Solomon, House |
| Walton Ranch |
| Walworth County Courthouse |
| Ward, Alonzo, Hotel |
| Ward, Elbert and Harriet, Ranch |
| Washington High School |
| Washington School |
| Watertown Commercial Historic District |
| Watertown Post Office |
| Watertown Stadium |
| Weigandt Barn |
| Wek Farmstead |
| Welch, Laura M, House |
| Welch, L. J., House |
| Welsh Presbyterian Church |
| Wenke, John G., House |
| Wenona Hall and Wecota Hall |
| Werth, Gustav and Mary, House |
| Wesch, Phillip, House |
| Wessington Springs Carnegie Library |
| Wessington Springs Opera House |
| Western Union Building |
| Wewela Hall |
| Whitewood Historic District |
| Whitney, Mary, House |
| Whittier School |
| Wide Awake Grocery Building |
| Wientjes Barn and Ranch Yard |
| Willey, E. H., House |
| Will, H.P., House |
| Williams, John and Kittie, House |
| Williams Piano Company House |
| Willow Grove Farm |
| Willson, Walter, House |
| Wind Cave National Park Administrative and Utility Area Historic District |
| Wolzmuth, John, House |
| Woodbine Cottage |
| Woodbine Cottage Experimental Rammed Earth Wall |
| Woodmen Hall |
| Woonsocket State Bank |
| Yankton Carnegie Library |
| Yankton High School Historic District |
| Young, Edna and Ernest, Ranch |
| Yusten House |
| ZCBJ Hall |
| Zech Farmstead |
| Ziebach County Courthouse |
| Zion Emmanuel Lutheran Church |
| Zoar Norwegian Lutheran Church |
Data from United States Park Service and Wikidata