South Dakota - Role: District
| Roetzel, Ferdinand and Elizabeth, Ranch |
| Schmid, Mathias, Farm |
| Scotland Main Street Historic District |
| Scotland Residential Historic District |
| Sexauer Seed Company Historic District |
| Sherman Historic District |
| Sioux Falls Downtown Historic District |
| Sittner Farm |
| Slip Up Creek Homestead |
| Soper-Behymer Ranch |
| South Dakota School for the Blind |
| Spearfish Fisheries Center |
| Spearfish Historic Commercial District |
| Split Rock Creek Park Historic District |
| Stearns, William, Ranch |
| Stevens Ranch |
| St. Francis Mission |
| St. Peter's Catholic Church |
| Streeter, Norman B., Homestead |
| Sturgis Commercial Block |
| Sturgis Water Works Company Supply Works Site |
| Terrace Park and Japanese Gardens |
| Thompson Farmstead |
| Tolefsons Beef Stock Farm |
| Tucek-Sykora Farmstead |
| University Historic District |
| University of South Dakota Historic Core District |
| Viken, Nicholas Augustus, Homestead |
| Vostad Farm |
| Walton Ranch |
| Ward, Elbert and Harriet, Ranch |
| Watertown Commercial Historic District |
| Wek Farmstead |
| Whitewood Historic District |
| Willow Grove Farm |
| Wind Cave National Park Administrative and Utility Area Historic District |
| Yankton College Historic District |
| Yankton High School Historic District |
| Yankton Historic Commercial District |
| Yankton Historic District |
| Young, Edna and Ernest, Ranch |
| Zech Farmstead |
Data from United States Park Service and Wikidata
