South Dakota - Area of significance: Commerce
| Aberdeen Highlands Historic District |
| Bank of Bowdle |
| Belle Fourche Commercial Historic District |
| Brookings Commercial Historic District |
| Brown Palace Hotel |
| Brown's Post |
| Caldwell, W. A., House |
| Calumet Hotel |
| Campbell, Colin, Post |
| Campbell Park Historic District of Huron |
| Carpenter Hotel |
| Cathedral Historic District |
| Central Block |
| Citizens State Bank of Henry |
| Deadwood Historic District |
| Dell Rapids Historic District |
| Delmont State Bank |
| Dickey, Walter, House |
| Doland Commercial Historic District |
| Downtown Vermillion Historic District |
| Drees Brothers General Mechandise |
| Engel Hotel |
| Farmers State Bank of Platte |
| First National Bank Building of Vermillion |
| First National Bank, Freeman |
| First National Bank of Garretson |
| First State Bank Building |
| First State Bank of Hazel |
| Fishback House |
| Fort Manuel |
| Fort Pierre Chouteau Site |
| Fowler Hotel |
| Fruitdale Store |
| Gale Buildings |
| Gambrill Storage Building |
| Golden Rule Department Store |
| Gregory County State Bank |
| Gurney, Charles, Hotel |
| Habicht & Habicht Department Store |
| Halloran-Matthews-Brady House |
| Harney Peak Hotel |
| Hilger Block |
| Hoover Store |
| Hot Springs Historic District |
| House of Gurney Historic District |
| Hyde Buildings |
| Inman House |
| Kant Hotel |
| Karcher Block |
| Keystone Trading Company Store |
| Kliegle Garage |
| Kroll Meat Market and Slaughterhouse |
| Kuehn, Andrew, Warehouse |
| L & A Baking Company |
| Lemmon Petrified Park |
| Little Missouri Bank Building |
| Lown, William Ernest, House |
| Martilla-Pettingel and Gorder General Merchandise Store |
| McEachron, C. E., General Merchandise |
| Miller, L. D., Funeral Home |
| Minneapolis Brewing Company Beer Warehouse |
| Mundt, John, Building |
| Municipal Building-City Hall |
| Murdo State Bank |
| Mystic Townsite Historic District |
| Nansen Store |
| Nick's Hamburger Shop |
| Norway Center Store |
| Ohlman-Shannon House |
| Old Courthouse and Warehouse Historic District |
| Old Yankton Bridge |
| Ortman Hotel |
| Pearl Hotel |
| Pettigrew, R. F., and Tate, S. L., Building |
| Phillips Block |
| Plumbing Supply Company |
| Pratt & Cjolme Building |
| Queen Bee Mill |
| Randolph, Dr. Fredrich A., Block |
| Rapid City Fruit Company |
| Rapid City Garage |
| Rapid City Historic Commercial District |
| Rapid City West Boulevard Historic District |
| Raymond Farmers and Citizens State Bank |
| Redwater Bridge, Old |
| Robar Trading Post |
| Scotland Main Street Historic District |
| Security Bank Building |
| Security State Bank |
| Security State Bank of Dante |
| Shriver-Johnson Building |
| Sioux Falls Downtown Historic District |
| Sioux Falls National Bank Building |
| Sorum Cooperative Store |
| Sorum Hotel |
| South Dakota Department of Transportation Bridge No. 06-129-020 |
| South Dakota Department of Transportation Bridge No. 51-051-000 |
| South Dakota Department of Transportation Bridge No. 63-052-030 |
| South Dakota Department of Transportation Bridge No. 63-197-130 |
| South Dakota Department of Transportation Bridge No. 63-198-181 |
Data from United States Park Service and Wikidata
