South Dakota - Area of significance: Architecture
| Potter County Courthouse |
| Prentis Park |
| Pringle House |
| Puhlman Farm |
| Pyle House |
| Quamman, Ole, House |
| Quillian, Thomas, House |
| Quinn, Michael, House |
| Raesly House |
| Randolph, Dr. Fredrich A., Block |
| Ranger Station |
| Rapid City Carnegie Library |
| Rapid City High School |
| Rapid City Historical Museum |
| Rapid City Historic Commercial District |
| Rapid City Laundry |
| Rapid City Masonic Temple |
| Rapid City West Boulevard Historic District |
| Raskob, Jacob and Elizabeth, Ranch |
| Raymond Farmers and Citizens State Bank |
| Redfield Carnegie Library |
| Redfield Light Plant and Fire Station |
| Renner Lutheran Sanctuary |
| Reynolds, Grant J., House |
| Reynolds, Joseph, Ranch Yard and Stage Stop |
| Rice Farm |
| Richards Cabins |
| Ries, Nicholas T., Farmstead |
| Riley, Almira, House |
| Ripple House |
| Rising Hail Colony |
| Roberts County Courthouse |
| Roslyn Auditorium |
| Rowe House |
| Royal Center School |
| Royhl, Adam and Minnie, House |
| Rudolph-Parke House |
| Ryman, Melchior, Farm |
| Saint Onge State Bank |
| Salem Church |
| Salem Church Parsonage |
| Sample-Lindblaum House |
| Savo Hall-Finnish National Society Hall |
| Schaffer Farmstead |
| Schatz, Jacob, House |
| Scheurenbrand, Gottlieb and Friederike, House |
| Schmid, Mathias, Farm |
| Schnaidt, Edward, House |
| Schnauber, Fred, House |
| Scotland Main Street Historic District |
| Scotland Residential Historic District |
| Scotland Royal Theater |
| Scotney, John Aaron, House |
| Scottish Rite Masonic Temple |
| Seaman, Louis N. and Helen, House |
| Security Bank Building |
| Security State Bank |
| Security State Bank of Dante |
| Sedlacek, Jacob, Chalkrock House |
| Sexauer, George P., House |
| Shafer Round Barn |
| Shakespeare Garden and Shay House |
| Shaw, Glenn W., House |
| Sherman Historic District |
| Shevling, L. W., Ranch |
| Shriver-Johnson Building |
| Sievers School |
| Simmons House |
| Simonson Farmstead |
| Singsaas Lutheran Church |
| Sioux Falls Downtown Historic District |
| Sioux Falls National Bank Building |
| Sisseton Carnegie Library |
| Sisseton School |
| Sittner Farm |
| Skartvedt House |
| Slettebak Grocercies, Hardware and Opera House |
| Slip Up Creek Homestead |
| Sloan, John, Homestead |
| Small, Charles and Eleanor, House |
| Smith, Jessie, Farmstead |
| Smith, William P., House |
| Snyder, L. E., House |
| Soldiers & Sailors World War Memorial |
| Soper-Behymer Ranch |
| Sorum Cooperative Store |
| Sorum Hotel |
| South Dakota Dept. of Transportation Bridge No. 25-380-142 |
| South Dakota School for the Deaf |
| South Dakota State Capitol |
| South Dakota State Penitentiary Historic Buildings |
| Spearfish Historic Commercial District |
| Spearfish Post Office (Old) |
| Spink County Courthouse |
| Split Rock Creek Park Historic District |
| Spring Creek School |
| Springer, R. D. and Mary, House |
| Stadum-Green House |
| St. Agnes Catholic Church |
| St. Agnes Church |
Data from United States Park Service and Wikidata
