South Carolina - Criteria: A (event)
| Retreat Rosenwald School |
| Richland Cemetery |
| Richland Cotton Mill |
| Richland Presbyterian Church |
| Richmond Hill Plantation Archeological Sites |
| Richmond Plantation |
| Ridge Hill High School |
| Ridgeway Historic District |
| Rip Raps Plantation |
| Rivers Bridge State Park |
| Rock Hill Body Company |
| Rock Hill Downtown Historic District |
| Rock Hill Printing and Finishing Company |
| Rockton and Rion Railroad Historic District |
| Rockville Historic District |
| Roper House Complex |
| Rose Hill |
| Roselawn |
| Rosemary Hall |
| Ruff's Chapel |
| Rural Hall Plantation House |
| Russell House |
| Russell, Nathaniel, House |
| Saint Thomas' Protestant Episcopal Church |
| Salem Black River Presbyterian Church |
| Salley Historic District |
| Saluda Factory Historic District |
| Saluda Theatre |
| Santee Canal |
| Scheper, F.W., Store |
| Scott House |
| Seaboard Air Line Railway Depot |
| Seaboard Air Line Railway Depot in McBee |
| Seaboard Air Line Railway Depot in Patrick |
| Seabrook, John, Plantation Bridge |
| Seacoast Packing Company |
| Seashore Farmers' Lodge No. 767 |
| Seaside Plantation |
| Seaside School |
| Secessionville Historic District |
| Selkirk Farm |
| Senn's Grist Mill-Blacksmith Shop-Orange Crush Bottling Plant |
| Sharon Downtown Historic District |
| Sheldon Church Ruins |
| Sheriff Mill Complex |
| Shiloh Methodist Church |
| Shivar Springs Bottling Company Cisterns |
| Sidney Park Colored Methodist Episcopal Church |
| Siloam School |
| Silver Bluff |
| Simkins, Modjeska Monteith, House |
| Sinclair Service Station |
| Site of Old Charles Towne |
| Slave Houses, Gregg Plantation |
| Slave Street, Smokehouse, and Allee, Boone Hall Plantation |
| Smalls, Robert, School |
| Smith Barn |
| Smith's Tavern |
| Smyrna Baptist Church |
| Snow's Island |
| Socastee Historic District |
| South Carolina Governor's Mansion |
| South Carolina National Bank of Charleston |
| South Carolina State Armory |
| South Carolina State Arsenal |
| South Carolina State College Historic District |
| South Carolina State Hospital, Mills Building |
| South Carolina Statehouse |
| South Carolina Western Railway Station |
| Southern Bleachery and Print Works |
| Southern Cotton Oil Company |
| Southern Railway Depot |
| Southern Railway Passenger Depot |
| Southern Railway Passenger Station |
| South Harper Historic District |
| South Street-South Church Street Historic District |
| Spartanburg Historic District |
| Spratt Cemetery |
| Springfield High School |
| Springfield Plantation House |
| Springwood Cemetery |
| SS WILLIAM LAWRENCE Shipwreck Site |
| Standard Oil Company Headquarters |
| St. Andrews Episcopal Church |
| Stateburg Historic District |
| St. David's Episcopal Church and Cemetery |
| Stevens-Dorn Farmstead |
| St. Helena Parish Chapel of Ease Ruins |
| St. James Episcopal Church, Santee |
| St. James the Greater Catholic Mission |
| St. John's Historic District |
| St. John's Lutheran Church |
| St. John's Lutheran Church |
| St. Luke's Parish Zion Chapel of Ease Cemetery |
| St. Mark's Church |
| St. Mary Help of Christians Church |
| St. Mary's Roman Catholic Church |
| Stockade, The |
| Stono River Slave Rebellion Site |
| St. Paul Camp Ground |
Data from United States Park Service and Wikidata
