South Carolina - Area of significance: Social History
| Abbeville Opera House |
| Aiken Mile Track |
| Aiken Training Track |
| All Saints' Episcopal Church, Waccamaw |
| All Star Bowling Lane |
| Amelia Street Historic District |
| American Legion Hut |
| Appin |
| Ashwood School Gymnasium and Auditorium |
| Babcock Building, South Carolina State Hospital |
| Bamberg, Gen. Francis Marion, House |
| Barnwell, Arthur, House |
| Barnwell House |
| Batesburg Commercial Historic District |
| Beaufort Historic District |
| Bedenbaugh, Jacob, House |
| Beneventum Plantation House |
| Bethel Presbyterian Church |
| Biggin Church Ruins |
| Brookgreen Gardens |
| Brown, Dianna, Antique Shop |
| Buck's Upper Mill Farm |
| Burt, Armistead, House |
| Calhoun Mill |
| Calhoun, Patrick, Family Cemetery |
| Carroll Place |
| Cattle Creek Campground |
| Cedar Grove Plantation Chapel |
| Cedar Springs Historic District |
| Century House |
| Chamber of Commerce Building |
| Chapel of Hope |
| Charleston Cemeteries Historic District |
| Charleston Navy Yard Officers' Quarters Historic District |
| Charleston's French Quarter District |
| Chicora Wood Plantation |
| Chinaberry |
| Church Street Historic District |
| Coffin Point Plantation |
| Coffin Point Plantation Caretaker's House |
| Coker Spring |
| Colonial Village Apartments |
| Columbia Historic District II |
| Columbia Township Auditorium |
| Coming Street Cemetery |
| Converse College Historic District |
| Converse Heights Historic District |
| Cook's Old Field Cemetery |
| Cooper River Historic District |
| Cornell Arms |
| Cuthbert, John A., House |
| Daufuskie Island Historic District |
| Davidson Hall, Coker College |
| Dock Street Theatre |
| Donalds Grange No. 497 |
| Earle, Col. Elias, Historic District |
| East Home Avenue Historic District |
| Ebony Guest House |
| Eddings Point Community Praise House |
| Elmwood Park Historic District |
| Enston, William, Home |
| Epps-McGill Farmhouse |
| Erwin House |
| Fenwick Hall |
| Florence Crittenton Home |
| Foster's Tavern |
| Friendfield Plantation |
| Gallman High School |
| Gilreath's Mill |
| Good Samaritan-Waverly Hospital |
| Goodson, Arthur, House |
| Goodwill Plantation |
| Graniteville Historic District |
| Great Falls Depot |
| Green's Funeral Home and Ambulance Service |
| Green, The |
| Hagood Mill |
| Hampton-Pinckney Historic District Extension |
| Harden Street Substation |
| Hart, John L., House |
| Hartley House |
| Hebron Presbyterian Church |
| Hickory Valley Historic District |
| Hicks, Zeno, House |
| Hightower Hall |
| Hobcaw Barony |
| Holman’s Barber Shop |
| Hopkins Family Cemetery |
| House of Peace Synagogue |
| Houser, David, House |
| Jackson Street Freedman's Cottages |
| Jamestown Historic District |
| Jenkins, Mary, Community Praise House |
| John's Island Presbyterian Church |
| Keithfield Plantation |
| King Cemetery |
| Knights of Wise Men Lodge |
| Lace House |
| Lancaster County Jail |
| Lancaster Presbyterian Church |
Data from United States Park Service and Wikidata
