South Carolina - Area of significance: Military
| Anchorage, The |
| Arsenal Hill |
| Banksia Hall |
| Barnwell-Gough House |
| Battery Cheves |
| Battery Gadsden |
| Battery LeRoy |
| Battery No. 1 |
| Battery No. 5 |
| Battery Thomson |
| Battery Tynes |
| Battery White |
| Battery Wilkes |
| Battle of Blackstock's Historic Site |
| Battle of Hanging Rock Historic Site |
| Beaufort Historic District |
| Beaufort National Cemetery |
| Biggin Church Ruins |
| Bonham House |
| Borough House Plantation |
| Boykin Mill Complex |
| Brattonsville Historic District |
| Brookgreen Gardens |
| Buford's Massacre Site |
| Burt, Armistead, House |
| Butler Family Cemetery |
| Calhoun, Patrick, Family Cemetery |
| Camden Battlefield |
| Camp Hill |
| Castle Pinckney |
| Cedar Bluff |
| Century House |
| Charlesfort-Santa Elena Site |
| Charleston Naval Hospital Historic District |
| Charleston Navy Yard Historic District |
| Charleston Navy Yard Officers' Quarters Historic District |
| Chicora Wood Plantation |
| Church of the Holy Apostles Rectory |
| Citadel Shirt Corporation |
| City of Camden Historic District |
| Coffin Point Plantation |
| Columbia Historic District I |
| Columbia Historic District II |
| """Congarees"" Site" |
| Cowpens National Battlefield |
| Cross Keys House |
| Cuthbert, John A., House |
| Dantzler, Col. Olin M., House |
| Darby Plantation |
| Daufuskie Island Historic District |
| Ebenezer Associate Reformed Presbyterian Church |
| Edgefield Historic District |
| Eutaw Springs Battleground Park |
| Florence National Cemetery |
| Folly North Site-38CH1213 |
| Fort Frederick |
| Fort Fremont Battery |
| Fort Fremont Hospital |
| Fort Howell |
| Fort Johnson/Powder Magazine |
| Fort Lyttelton Site |
| Fort Mitchel |
| Fort Moore-Savano Town Site |
| Fort Motte Battle Site |
| Fort Moultrie Quartermaster and Support Facilities Historic District |
| Fort Palmetto |
| Fort Pemberton Site |
| Fort Pringle |
| Fort Sumter National Monument |
| Fort Trenholm |
| Georgetown Historic District |
| Georgetown Lighthouse |
| Gillisonville Baptist Church |
| Guillebeau House |
| Hammond, Charles, House |
| Historic Camden Revolutionary War Restoration |
| H. L. HUNLEY (submarine) |
| Honey Hill-Boyd's Neck Battlefield |
| Horn Creek Baptist Church |
| Jennings-Brown House |
| Kelley, Jacob, House |
| Kincaid-Anderson House |
| Kings Mountain National Military Park |
| Landsford Canal |
| Lewisfield Plantation |
| Lindley's Fort Site |
| Marine Barracks, Charleston Navy Yard |
| Marion Historic District |
| McLeod Plantation |
| Mount Dearborn Military Reservation |
| Mount Pleasant Historic District |
| Mulberry Plantation (Chesnut House) |
| Musgrove's Mill Historic Battle Site |
| National Guard Armory |
| Newberry Historic District |
| Ninety Six National Historic Site |
| Oaks, The |
| Old Cokesbury and Masonic Female College and Conference School |
| Old Dorchester |
| Old Stone Church and Cemetery |
Data from United States Park Service and Wikidata