South Carolina - Area of significance: Education
| Abbeville County Training School |
| Allendale Training School |
| Allen University |
| Anderson College Historic District |
| Anderson Historic District |
| Benedict College Historic District |
| Benson, Florence C., Elementary School |
| Berly, William, House |
| Bettis Academy and Junior College |
| Borough House Plantation |
| Brattonsville Historic District |
| Burroughs School |
| Caldwell-Johnson-Morris Cottage |
| Carnegie Public Library |
| Carroll Rosenwald School |
| Catawba Rosenwald School |
| Central Graded School |
| Central High School |
| Charleston Historic District |
| Cherry Hill School |
| Chicora Wood Plantation |
| Citizens and Southern National Bank of South Carolina |
| Claflin College Historic District |
| Clemson College Sheep Barn |
| Clemson University Historic District I |
| Clemson University Historic District II |
| Columbia Historic District II |
| Converse College Historic District |
| Coulter Memorial Academy Historic District |
| Davidson Hall, Coker College |
| Davis, Winnie, Hall |
| Dennis High School |
| Dillon Graded School and Dillon Public School |
| Dovillers-Manning-Magoffin House |
| Dukes Gymnasium |
| Duncan, Bishop William Wallace, House |
| Easley High School Auditorium |
| Ebenezer Academy |
| Eden Hall |
| Edgewood School |
| Erskine College-Due West Historic District |
| Fair-Rutherford and Rutherford Houses |
| Faith Cabin Library at Anderson County Training School |
| Faith Cabin Library at Seneca Junior College |
| Finley High School |
| Florence Public Library |
| Fountain Inn Principal's House and Teacherage |
| Fox House |
| Frogmore Plantation Complex |
| Furman Institution Faculty Residence |
| Gallman High School |
| Georgetown Historic District |
| Gifford Rosenwald School |
| Goodwill Parochial School |
| Great Branch Teacherage |
| Hall, Ainsley, House |
| Hampton Colored School |
| Hampton-Pinckney Historic District |
| Hampton-Preston House |
| Hannah Rosenwald School |
| Harbison College President's Home |
| Hodge Hall |
| Holly Springs School |
| Holy Cross Faith Memorial School |
| Hope Rosenwald School |
| Hopewell Rosenwald School |
| Hopkins Graded School |
| Howard Junior High School |
| Kumler Hall |
| Lander College Old Main Building |
| Latimer High and Elementary School |
| Leesville College Historic District |
| Liberty Colored High School |
| Liberty Universalist Church and Feasterville Academy Historic District |
| Limestone Springs Historic District |
| Lincoln High School |
| Long Creek Academy |
| Lowman Hall, South Carolina State College |
| Magnolia |
| Marion Historic District |
| Marlboro County Training School |
| Marysville School |
| McCorkle-Fewell-Long House |
| McCoy Farmstead |
| McDowell Site |
| McMaster School |
| Meggett, W. Gresham, High and Elementary School |
| Memorial Hall |
| Middleton Place |
| Mt. Zion Institute High School |
| Mt. Zion Rosenwald School |
| Newberry College Historic District |
| Nicholson, James, House |
| Oaks, The |
| Ocean Grove School |
| Old Batesburg-Leesville High School |
| Old Campus District, University of South Carolina |
| Old Cokesbury and Masonic Female College and Conference School |
| Old Greenwood High School |
| Old Market Building |
Data from United States Park Service and Wikidata
