South Carolina - Area of significance: Black Heritage
| McGhee Block |
| McLeod Plantation |
| Meggett, W. Gresham, High and Elementary School |
| Mosquito Beach Historic District |
| Mount Carmel A.M.E. Zion Campground |
| Mount Prospect Baptist Church |
| Moving Star Hall |
| Mt. Olive Baptist Church |
| Mt. Pisgah A.M.E. Church |
| Mt. Pisgah Baptist Church |
| Mt. Zion Rosenwald School |
| Mulberry Chapel Methodist Church |
| North Carolina Mutual Building |
| Oaks, The |
| Ocean Grove School |
| Old Bethel United Methodist Church |
| Old Pilgrim Baptist Church Cemetery and Kilgore Family Cemetery |
| Old Slave Mart |
| Orangeburg City Cemetery |
| Pee Dee River Rice Planters Historic District |
| Penn Center Historic District |
| Phillips Community Historic District |
| Pine Grove Rosenwald School |
| Pleasant Grove School |
| Poinsett State Park Historic District |
| Progressive Club, The |
| Rainey, Joseph H., House |
| Randolph Cemetery |
| Retreat Rosenwald School |
| Richland Cemetery |
| Richmond Hill Plantation Archeological Sites |
| Ridge Hill High School |
| Ruffin High and Elementary School |
| Ruth's Beauty Parlor |
| Sadler Store |
| Saint Thomas' Protestant Episcopal Church |
| Sandy Island School |
| Scott’s Branch High School |
| Seashore Farmers' Lodge No. 767 |
| Seaside Plantation |
| Seaside School |
| Selkirk Farm |
| Sidney Park Colored Methodist Episcopal Church |
| Simkins, Modjeska Monteith, House |
| Sims High School |
| Slave Houses, Gregg Plantation |
| Slave Street, Smokehouse, and Allee, Boone Hall Plantation |
| Smalls, Robert, House |
| Snee Farm-Charles Pinckney National Historic Site |
| Spann, Dr. Cyril O., Medical Office |
| St. George Rosenwald School |
| St. James the Greater Catholic Mission |
| Stoney-Baynard Plantation |
| Stono River Slave Rebellion Site |
| St. Paul Camp Ground |
| Summerton High School |
| Tingley Memorial Hall, Claflin College |
| Trapp and Chandler Pottery Site (38GN169) |
| Treadwell Street Historic District |
| Trinity Methodist Episcopal Church |
| Union Community Hospital |
| Unity Baptist Church |
| Vesey, Denmark, House |
| Voorhees College Historic District |
| Wade Hampton State Office Building |
| Washington. Booker T., High School Auditorium |
| Waverly Historic District |
| Wesley, John, Methodist Episcopal Church |
| Wesley Methodist Church |
| Williams, A.P., Funeral Home |
| Williams Chapel A.M.E. Church |
| Working Benevolent Temple and Professional Building |
| Zion Baptist Church |
Data from United States Park Service and Wikidata