South Carolina - Area of significance: Agriculture
| Anderson House |
| Annandale Plantation |
| Arcadia Plantation |
| Ashley Hall Plantation |
| Ashley River Historic District |
| Belle Isle Rice Mill Chimney |
| Bethea, Alpheus Victor and Martha Cooper, Farmstead |
| Big Lake Cattle Mound |
| Bleak Hall Plantation Outbuildings |
| Bonnie Shade |
| Borough House Plantation |
| Brady's Cattle Mound |
| Brattonsville Historic District |
| Brookgreen Gardens |
| Brooklands Plantation |
| Carnes, James, House |
| Cassina Point |
| Cattle Mound #6 |
| Chicora Wood Plantation |
| Clarkson Farm Complex |
| Clemson College Sheep Barn |
| Clemson University Historic District I |
| Clemson University Historic District II |
| Coffin Point Plantation |
| Cohasset |
| Coker Experimental Farms |
| Coker, S. Pressly, House |
| Columbia Commercial Historic District |
| Colvin-Fant-Durham Farm Complex |
| Cook's Lake Cattle Mound |
| Cooner's Cattle Mound |
| Cooper River Historic District |
| Cross Keys House |
| Culclasure-Geiger Farmstead |
| Darlington Industrial Historic District |
| Davis Plantation |
| Dead River Cattle Mound |
| Dead River Dike |
| Denver Downs Farmstead |
| Dew Barn |
| Dillard Barn |
| Eden Hall |
| Edgefield Historic District |
| Ellerbe's Mill |
| Fairfield Plantation |
| Fairfield Rice Mill Chimney |
| Fonti Flora Plantation |
| Fraser, Thomas, House |
| Friendfield Plantation |
| Frogmore |
| Galivants Ferry Historic District |
| Goodwill Plantation |
| Grove Plantation |
| Hagood Mill |
| Harrietta Plantation |
| Hartley House |
| Hendrix, Henry Franklin, House |
| Hobcaw Barony |
| Hopewell Presbyterian Church and Hopewell Cemetery |
| Hopkins Farm |
| House Plantation, Old |
| Hurricane Tavern |
| Jamestown Historic District |
| Keil Farm |
| Keithfield Plantation |
| Kensington Plantation House |
| Kincaid-Anderson House |
| Kirkland, B. B., Seed and Distributing Company |
| Koon, John Jacob Calhoun, Farmstead |
| Laurel Bay Plantation |
| Laurens Historic District |
| Lawson's Pond Plantation |
| Loch Dhu |
| Manor, The |
| Mansfield Plantation |
| Manship Farmstead |
| McCoy Farmstead |
| McLaurin-Roper-McColl Farmstead |
| McLeod Farmstead |
| McMakin's Tavern |
| McPhail Angus Farm |
| Medway |
| Middleton Place |
| Midway Plantation |
| Milldam Rice Mill and Rice Barn |
| Millwood |
| Murrells Inlet Historic District |
| Nightingale Hall Rice Mill Chimney |
| Oak Island |
| Oaklyn Plantation |
| Oakwood |
| Ocean Grove School |
| Old Batesburg Grade School |
| Old Market Building |
| Orangeburg County Fair Main Exhibit Building |
| Pee Dee River Rice Planters Historic District |
| Pendleton Historic District |
| Pomaria |
| Price's Post Office |
| Prospect Hill |
Data from United States Park Service and Wikidata
