Pennsylvania - Area of significance: Transportation
| Seventh Street Bridge |
| Shaffer's Bridge |
| Sheard's Mill Covered Bridge |
| Shearer's Covered Bridge |
| Shenk's Mill Covered Bridge |
| Ship Inn |
| Shoemaker Covered Bridge |
| Shrewsbury Historic District |
| Shrewsbury Railroad Station, Stewartstown Railroad |
| Shriver Covered Bridge |
| Sixteenth Street Bridge |
| Sixth Street Bridge |
| Snooks Covered Bridge |
| Snyder, Caspar, House |
| Snyder Covered Bridge No. 17 |
| Sonestown Covered Bridge |
| South Perkasie Covered Bridge |
| South Road Bridge, Northern Central Railway |
| South Tenth Street Bridge |
| Southwark Municipal Piers |
| Speakman No. 1 |
| Speakman No. 2, Mary Ann Pyle Bridge |
| Sprowl's Covered Bridge |
| Square Tavern |
| Staple Bend Tunnel |
| Starlight Station, New York, Ontario, and Western Railway |
| Steel Hopper Car No. 33164 |
| Steel Passenger Coach No. 1650 |
| Steel Passenger Coach No. 1651 |
| Stephens, Linton, Covered Bridge |
| Stewartstown Engine House, Stewartstown Railroad |
| Stewartstown Railroad Station |
| Stillwater Covered Bridge No. 134 |
| St. Mary's Covered Bridge |
| Stoddartsville Historic District |
| Stone Arch Road Bridge, Stewartstown Railroad |
| Stouchsburg Historic District |
| Stoystown Historic District |
| Strafford Railroad Station |
| Strasburg Historic District |
| Suburban Station Building |
| Sunbury Historic District |
| Switcher No. 1670 |
| Switcher No. 94 |
| Thomas Covered Bridge |
| Thomas Mill Covered Bridge |
| Trenton City/Calhoun Street Bridge |
| Trusal Covered Bridge |
| Tulpehocken Station Historic District |
| Tunkhannock Viaduct |
| Twin Bridges-East Paden Covered Bridge No. 120 |
| Twin Bridges-West Paden Covered Bridge No. 121 |
| Uhlerstown Historic District |
| Union Canal Tunnel |
| Uniontown Downtown Historic District |
| Unionville Historic District |
| Upper Roxborough Historic District |
| Valley Road Bridge, Stewartstown Railroad |
| Van Sant Covered Bridge |
| Vaughan, Rev. Joshua, House |
| Waggoner Covered Bridge |
| Wagner Covered Bridge No. 19 |
| Walnut Street Bridge |
| Walter's Mill Bridge |
| Walton, Asa, House |
| Wanich Covered Bridge No. 69 |
| Waterford Covered Bridge |
| Weaver's Mill Covered Bridge |
| Wehr Covered Bridge |
| Wertz's Covered Bridge |
| West Alexander Historic District |
| Western Division of the PA Canal |
| Western Division-Pennsylvania Canal |
| Westinghouse, George, Memorial Bridge |
| West Philadelphia Passenger Railway Company Carhouse |
| White Covered Bridge |
| White Horse Tavern |
| White Rock Forge Covered Bridge |
| Wilkinsburg Historic District |
| Williams Deluxe Cabins |
| Wilson's Mill Covered Bridge |
| Wooden Baggage Express No. 6 |
| Wooden Express Baggage No. 6076 |
| Wooden Hopper Gondola No. 1818 |
| Woodland Station |
| Woods, Nettie, Covered Bridge |
| Wright, Cerl, Covered Bridge |
| Wrightsville Historic District |
| Wycombe Village Historic District |
| Wyit Sprowls Covered Bridge |
| Yardley Historic District |
| Y Covered Bridge No. 156 |
| Young, Robert, House |
| Zook's Mill Covered Bridge |
Data from United States Park Service and Wikidata
