Pennsylvania - Area of significance: Education
| Rittenhouse, David, Junior High School |
| Roosevelt, Theodore, Junior High School |
| Ruter Hall |
| Ryerss Mansion |
| Saturday Club |
| Schenley Farms Historic District |
| Schenley High School |
| Schiller Elementary School |
| Selinsgrove Hall and Seibert Hall |
| Shaw, Anna Howard, Junior High School |
| Sheads House |
| Shelly School |
| Shelly, William, School and Annex |
| Siegfried's Dale Farm |
| Silver Lake Schoolhouse #1 |
| Simpson Street School |
| Sixth Ward School |
| Sodom Schoolhouse |
| Southampton Baptist Church and Cemetery |
| South Side High School |
| South Ward School |
| Spruce Grove School |
| St. Anthony de Padua Parish School |
| Stanton, M. Hall, Public School |
| Steelton High School |
| St. Elizabeth's Convent |
| Sterrett Sub-District School |
| Stevens High School |
| Stevens School |
| Stevens, Thaddeus, School of Observation |
| St. Joseph's Parish Complex |
| Stouchsburg Historic District |
| St. Peter's Cathedral Complex |
| Strode's Mill Historic District |
| Sugartown Historic District |
| Sulzberger, Mayer, Junior High School |
| Summit Hill High School |
| Sutton, John, Hall |
| Thomas, M. Carey, Library, Bryn Mawr College |
| Thompson, S. R., House |
| Trimbleville Historic District |
| Troy Public High School |
| Tuscarora Academy |
| Union Library Company |
| Union School |
| University of Pennsylvania Campus Historic District |
| Vare, Edwin H., Junior High School |
| Villa Maria Academy |
| Wagner Free Institute of Science |
| Walt Disney Elementary School |
| Washington Vocational School |
| Wellsville Historic District |
| West Chester Boarding School for Boys |
| West Chester State College Quadrangle Historic District |
| West Philadelphia High School |
| White Hall of Bristol College |
| Williamson Free School of Mechanical Trades |
| Williams, Roger, Public School No. 10 |
| Wilmot, David, School |
| Wilson College |
| Wollner Building |
| Woman's Medical College of Pennsylvania |
| Woolslair Elementary School |
| Wrightstown Octagonal Schoolhouse |
| Wyoming Seminary |
Data from United States Park Service and Wikidata
