Pennsylvania - Area of significance: Architecture
| Dykeman's Spring |
| Eagle Hotel |
| Eagles Mere Historic District |
| Eagle Tavern |
| Eakin, John, Farm |
| East Berlin Historic District |
| East Bradford Boarding School for Boys |
| East Carson Street Historic District |
| East Center City Commercial Historic District |
| East Lancaster Avenue Historic District |
| East Liberty Commercial Historic District |
| East Liberty Market |
| East, Nicholas, House |
| Easton Historic District |
| Easton House |
| East Stroudsburg Armory |
| East Stroudsburg Railroad Station |
| East Washington Historic District |
| East York Historic District |
| Ebensburg Historic District |
| Eberhardt and Ober Brewery |
| Eberly, Johannes, House |
| Eby Shoe Corporation |
| Eckley Historic District |
| Economy Historic District |
| Edgemont |
| Edgewood |
| Edmunds, Henry R., School |
| Egg Hill Church |
| Ehrenhardt, Jacob Jr., House |
| Ehrhart's Mill Historic District |
| Eichelberger High School |
| Eisenlohr-Bayuk Tobacco Historic District |
| Elder, Abraham, Stone House |
| Electric Locomotive No. 4859 |
| Elfreth's Alley Historic District |
| Elkins Railroad Station, Philadelphia and Reading Railroad |
| Ellicott, Andrew, House |
| Elliott, S. B., State Park Day Use District |
| Elliott, S. B., State Park Family Cabin District |
| Elm Court |
| Elmridge |
| Elmwood Park Historic District |
| Elverson Historic District |
| Elverson, James, Jr., School |
| Ely, Joshua, House |
| Embassy Theatre |
| Emig Mansion |
| Emlenton Historic District |
| Emmanuel Episcopal Church |
| Engine Company No. 29 |
| Englehardt, John, Homestead |
| Ephrata Cloister |
| Ephrata Commercial Historic District |
| Equinunk Historic District |
| Equitable Trust Building |
| Ercildoun Historic District |
| Erie Armory |
| Erie Federal Courthouse and Post Office |
| Erie Land Lighthouse |
| Erie Masonic Temple |
| Erie Railroad Station |
| Erie Trust Company Building |
| Erpff, Philip, House |
| Esherick, Margaret, House |
| Esherick, Wharton, Studio |
| Estey Hall |
| Evans, Ann Cunningham, House |
| Evans, Benjamin, House |
| Evansburg Historic District |
| Evans, William and Mordecai, House |
| Everett Historic District |
| Evergreen Hamlet |
| Everhart, William, House |
| Ewart Building |
| Exton Hotel |
| Eyre, Wilson, House |
| Fagley House |
| Fairelawn |
| Fairfax Apartments |
| Fairfield Historic District |
| Fairfield Inn |
| Fairmount Avenue Historic District |
| Fairmount Historic District |
| Fairmount Park |
| Fairmount Water Works |
| Fairville Historic District |
| Fallingwater |
| Fallsington Historic District |
| Farmers and Mechanics Trust Company Building |
| Farmers' High School |
| Farmers Market |
| Farmer's Southern Market |
| Farragut, David, School |
| Fayette School |
| Fayette-Springs Hotel |
| Federal Barn |
| Federal Row |
| Federal School |
| Federal Street School |
Data from United States Park Service and Wikidata
