Pennsylvania - Area of significance: Architecture
| Stirling, Maj. Gen. Lord, Quarters |
| St. James Episcopal Church |
| St. James Hotel |
| St. John's Church |
| St. John's Evangelical Lutheran Church |
| St. John the Baptist Ukranian Catholic Church |
| St. John the Evangelist Roman Catholic Church and School Building |
| St. Joseph's House for Homeless Industrious Boys |
| St. Lukes Episcopal Church |
| St. Luke’s Episcopal Church & Throop Memorial Parish House |
| St. Mark's Episcopal Church |
| St. Mark's Episcopal Church |
| St. Mary's Episcopal Church |
| St. Marys Historic District |
| St. Michael's Protestant Episcopal Church, Parish House and Rectory |
| St. Nicholas Byzantine Catholic Church |
| Stoddartsville Historic District |
| Stoehr and Fister Building |
| Stoever, John Casper, Log House |
| Stonehaven |
| Stoner, Samuel, Homestead |
| Stonorov, Oskar G., House |
| Stotesbury Club House |
| Stouchsburg Historic District |
| Stout, Isaac, House |
| Stover, Isaac, House |
| Stover, Jacob, Farmstead |
| Stover Mill |
| Stoystown Historic District |
| St. Paul's Church |
| St. Paul's Episcopal Church |
| St. Paul's Union Church and Cemetery |
| St. Peter's Cathedral Complex |
| St. Peter's Church |
| St. Peter's Church |
| St. Peter's Church in the Great Valley |
| St. Peter's Episcopal Church and Rectory |
| St. Peter's Episcopal Church of Germantown |
| St. Peter's Kierch |
| St. Peters Village Historic District |
| Strafford Railroad Station |
| Strasburg Historic District |
| Strassburger, Reuben and Elizabeth, Farmstead |
| Strawbridge and Clothier Store |
| Strickland-Roberts Homestead |
| Strickland, William, Row |
| Strickler Family Farmhouse |
| Strip Historic District |
| Strode's Mill |
| Strode's Mill Historic District |
| Struthers Library Building |
| St. Severin's Old Log Church |
| St. Stanislaus Kostka Roman Catholic Church |
| St. Stephen's Church |
| St. Stephen's Episcopal Church |
| St. Thomas Memorial Church |
| Stupp-Oxenrider Farm |
| Sturgis, Julius, Pretzel House |
| St. Vincent Archabbey Gristmill |
| Suburban Station Building |
| Suffolk Manor Apartments |
| Sugartown Historic District |
| Sullivan County Courthouse |
| Sullivan, James J., School |
| Sulzberger, Mayer, Junior High School |
| Summers, Lewis, Farm |
| Summit Hill High School |
| Summit Hotel |
| Sunbury Armory |
| Sunbury Historic District |
| Sun Oil Building |
| Susquehanna County Courthouse Complex |
| Sutton-Ditz House |
| Sutton, John, Hall |
| Swarr, John and Elizabeth, House |
| Swatara Ferry House |
| Swatara Furnace |
| Swedish Lutheran Parsonage |
| Swetland Homestead |
| Tabor Home for Needy and Destitute Children |
| Tabor Reformed Church |
| Tamaqua Historic District |
| Tannery, The |
| Taylor, Bayard, School |
| Taylor, Benjamin, Homestead |
| Taylor-Cope Historic District |
| Taylor House |
| Taylor, Peter, Farmstead |
| Taylor, Phillip, House |
| Taylorstown Historic District |
| Teller Brothers-Reed Tobacco Historic District |
| Temple-Webster-Stoner House |
| Terminal Commerce Building |
| Terracina |
| Thaddeus Kosciuszko National Memorial |
| Thayer-Thompson House |
| The Elverson Building |
| Third Presbyterian Church |
| Thirtieth Street Station |
| Thomas, Charles, House |
Data from United States Park Service and Wikidata