Oregon - Significance region: Local
| Shively-McClure Historic District |
| Shogren, Fred A., May, and Ann, House |
| Sholes, Albert S., House |
| Shone-Charley House |
| Shorey, Charles, House |
| Shute-Meierjurgen Farmstead |
| Sigglin, Charles O., Flats |
| Sigler House |
| Siletz Agency Site |
| Silsby, Col. William H., House |
| Silverton Commercial Historic District |
| Siskiyou-Hargandine Historic District |
| Sisters High School |
| Sixes Hotel |
| Skidmore Academy Historic District |
| Slade, J. E., House |
| Slater Building |
| Smeede Hotel |
| Smith, Alfred H. and Mary E., House |
| Smith, Andrew, House |
| Smith, Bernard Pitzer, House |
| Smith, E. L., Building |
| Smith, Henry Clay, House |
| Smith, Herbert and Katherine, House |
| Smith, James Alexander, and Elmarion, Barn and Lame-Smith House |
| Smith, John T., House |
| Smith, Mary J. G., House |
| Smith, Milton W., House |
| Smith, N. P., Pioneer Hardware Store |
| Smith-Ohmart House |
| Smith, Percy A., House |
| Smith, R. S., Motor Company Building |
| Smithson and McKay Brothers Blocks |
| Smith, Walter V., House |
| Soap Creek School |
| Soderberg, Peter and Bertha, House |
| Sod House Ranch |
| Sommerville, Edgar, House |
| Southern Pacific Passenger Depot |
| South First National Bank Block |
| South Main Street Commercial Historic District |
| South Oakdale Historic District |
| South Park Blocks |
| South Portland Historic District |
| Sovereign Hotel |
| Spalding Building |
| Sparta Building |
| Spaulding, Charles K., House |
| Speed's Place on the Rogue |
| Spence, Jack, House |
| Spencer, Arthur Champlin, and Margaret Fenton Spencer House |
| Sphier, D.H., Building |
| Spies-Robinson House |
| Spokane, Portland and Seattle Railroad Warehouse |
| Sprague-Marshall-Bowie House |
| Springdale School |
| Springfield General Hospital |
| Springfield High School |
| Springfield Motors Buick Dealership |
| Spring Valley Presbyterian Church |
| Spring Valley School |
| Staples, Norris, House |
| Starkey-McCully Block |
| Starr and Blakely Drug Store |
| Star Ranger Station |
| Star Ranger Station Building, Old |
| Starr, Edwin and Anna, House |
| St. Elizabeth Hospital (Old) |
| Stellmacher, Gus and Emma, Farmstead |
| Stephens Community Historic District |
| Stephens, James B., House |
| Stevens Building |
| Stevens, Charles, House |
| Stewart, LaSells D., House |
| St. Helens Downtown Historic District |
| Still-Perkins House |
| St. James Episcopal Church |
| St. Johns Signal Tower Gas Station |
| Stokes, Francis Marion, Fourplex |
| Stone Bridge and the Oregon Central Military Wagon Road |
| Storey, George Lincoln, House |
| Stover, B. A. and Ruth, House |
| St. Patrick's Roman Catholic Cemetery |
| St. Patrick's Roman Catholic Church and Rectory |
| St. Peter's Roman Catholic Church |
| St. Peter's Roman Catholic Church |
| Straight, Hiram A., House |
| Stratton, C. C., House |
| Stratton-Cornelius House |
| St. Thomas' Episcopal Church |
| Stuart, Dr., House |
| Sumpter Valley Railway Historic District |
| Superintendent's House |
| Sutherland, John, House |
| Sutherlin Bank Building |
| Svenson Blacksmith Shop |
| Swanson, Norman and Frances, House |
| Swedish Evangelical Mission Covenant Church |
| Sweeney, Dr. Charles T. and Mary, House |
| Sweeney, Straub and Dimm Printing Plant |
Data from United States Park Service and Wikidata
