Oklahoma - Significance region: Local
| Sayre Champlin Service Station |
| Sayre City Park |
| Sayre Downtown Historic District |
| Sayre-Mann House |
| Sayre Rock Island Depot |
| Schultz-Neal Stone Barn |
| Science Building |
| Science Hall |
| Scott Store |
| Seaba's Filling Station |
| Security National Bank |
| Seiling Milling Company |
| Selph Building |
| Seminole County Courthouse |
| Seminole High School |
| Seminole Municipal Building |
| Seminole Whipping Tree |
| Severs Block |
| Severs Hotel |
| Shady Point School |
| Sharp Lumberyard |
| Shattuck National Bank Building |
| Shawnee Friends Mission |
| Sheets House |
| Sheltered Shelter District |
| Shepherd Historic District |
| Sherman Machine and Iron Works Building |
| Shinn Family Barn |
| Sieber Grocery and Apartment Hotel |
| Silver City Cemetery |
| Simmons, Louis B., House |
| Sinclair Loading Rack |
| Sinclair Service Station |
| Sinopoulo, John, House |
| Sixth Street Commercial/Residential Historic District |
| Skullyville County Jail |
| Slaughter, Dr. W.H., House |
| Slippery Moss Shelter |
| Smallwood, Benjamin Franklin, House |
| Smith and Kernke Funeral Directors |
| Snow School |
| Soldani Mansion |
| Sooner Co-op Association Elevator (West) |
| Sophian Plaza |
| Southern Hotel |
| Southridge Addition Historic District |
| Southwestern Bell Main Dial Building |
| Southwestern Bell Telephone Building |
| Spanish Village Historic District |
| Spaulding School Gymnasium-Auditorium |
| Speer School |
| Spencerville School Campus |
| Spraker Service Station |
| Spring Dell School |
| Stanford Furniture Co. Building |
| St. Ann’s Home for the Aged |
| St. Anthony's Catholic Church |
| Starr Pasture Archeological Site (34SQ224) |
| State National Bank Building |
| St. Cloud Hotel |
| Stein, L. L., House |
| Stevens Rock Shelter |
| St. George Episcopal Church |
| Stigler School Gymnasium-Auditorium |
| Stillwater Santa Fe Depot |
| Stine Building |
| St James Episcopal Church |
| St. John Baptist Church and Rectory |
| St. John's Evangelical Lutheran Church |
| St. John Vianney Training School for Girls |
| St. Joseph's Catholic Church |
| Stock Exchange Bank |
| Stonebraker Heights Historic District |
| Stonegate Elementary School |
| Storm House |
| St. Paul Baptist Church and Cemetery |
| St. Paul's Cathedral |
| St. Philip's Episcopal Church |
| Strother Memorial Chapel |
| Stroud, James W., House |
| Stroud School, Old |
| Stroud Trading Company Building |
| St. Stephen's Episcopal Church |
| St. Thomas Primitive Baptist Church |
| Stuart Hotel |
| Sugg Clinic |
| Sulphur Armory |
| Summerfield School |
| Sumner School |
| Sunset-Vogue-Blue Ribbon Apartments Historic District |
| Sunshine Cleaners |
| Surety Building |
| Swan Lake Historic District |
| Tabor House |
| Taft City Hall |
| Taft Junior High School |
| Tahlequah Armory |
| Tahlequah Carnegie Library |
| Tall Cane Archeological Site (34SQ294) |
| Tamaha Jail and Ferry Landing |
Data from United States Park Service and Wikidata
