Arizona - Significance region: National
| San Xavier del Bac |
| San Ysidro Hacienda |
| Schoolhouse Point (AR-03-12-06-13(TNF) |
| Sierra Bonita Ranch |
| Silver Peak Lookout Complex |
| Smith, J. Homer, House |
| Smith, Professor George E. P., House |
| Standing Fall House |
| St. Michael's Mission |
| Stoffela Store/Railroad Exchange |
| St. Paul's Episcopal Church |
| Sunset Crater-Cinder Lake Apollo Mission Testing and Training Historic District |
| Sutherland Wash Archeological District |
| Sutherland Wash Rock Art District |
| Sycamore Cliff Dwelling |
| Taliesin West |
| Thirty-Fifth Parallel Route |
| Thompson, Boyce, Southwestern Arboretum |
| Tombstone City Hall |
| Tombstone Historic District |
| Tonto National Monument Archeological District |
| Tonto National Monument, Lower Ruin (AZ U:8:047A ASM) |
| Tonto National Monument, Upper Ruin (AZ U:8:048 ASM) |
| Tucson Community Center Historic District |
| Tumacacori Museum |
| Tumacacori National Monument |
| Tumamoc Hill Archeological District, The |
| Tuzigoot National Monument Archeological District |
| Twin Buttes Archeological District |
| Twins |
| University Indian Ruin Archeological Research District |
| Upper Davidson Canyon Archeological District |
| Urban Route 66, Williams |
| USDA Tucson Plant Materials Center |
| U.S. Inspection Office, Morley Gate-Nogales, Arizona |
| U.S. Inspection Station-Douglas, Arizona |
| U.S. Inspection Station-Sasabe, Arizona |
| Valencia Site (BB:13:15;BB:13:74) |
| Velasco House |
| Ventana Cave |
| Volunteer Lookout Cabin |
| Walnut Canyon National Monument |
| Warner, Solomon, House and Mill |
| Webb Peak Lookout Tower |
| Webster Auditorium |
| West Peak Lookout Tower |
| White Man Cave |
| Wigwam Village #6 |
| Winona |
| Wise Men |
| Woody Mountain Lookout Tower |
| Wrigley, William, Jr., Winter Cottage |
| Wupatki National Monument |
| Yuma City Hall |
| Yuma County Courthouse |
| Yuma Crossing and Associated Sites |
Data from United States Park Service and Wikidata