Ohio - Significance region: Local
| Dublin Veterinary Clinic |
| Duffy, Michael, Farm |
| Dunbar Historic District |
| Duncarrick |
| Dunham, Hezekiah, House |
| Dun, John, Homestead |
| Dunlap-Burnett-Moss House |
| Dunlap, William K., House |
| Dunns Pond Mound |
| Dunton House |
| Dustin Cabin |
| Duttenhofer Building |
| Eagle Cliff Hotel |
| Eagle Point Colony Historic District |
| Eagles Building |
| Eagles Building |
| Eagles Building-Strand Theater |
| Eagles Temple |
| Eagles' Temple |
| Eagle Township Works I Mound |
| Ealy, George and Christina, House |
| Earley-Hartzell House |
| Early Greek Revival Cottage |
| Early Greek Revival House |
| East 89th Street Historic District |
| East Boulevard Apartment House |
| East Boulevard Historic District |
| East Cleveland District 9 School |
| Eastern Hills Young Men's Christian Association (YMCA) |
| East Fifth Street Historic District |
| East Fork Site |
| East Fourth Street Historic District |
| East Fourth Street Historic District |
| Eastgate Apartments Historic District |
| East Liberty School, District No. 11 |
| East Liverpool Downtown Historic District |
| East Liverpool Pottery |
| East Main Street Historic District |
| East Main Street Historic District |
| East Market Street Church of Christ |
| East Market Street School |
| East North Broadway Historic District |
| East Ohio Building, The |
| East Ohio Gas Company Building |
| East Point Manor |
| East River Road Historic District I |
| East River Road Historic District II |
| East Second Street District |
| East Side Commercial Block |
| East Side Fire Station |
| East State Street-Elmwood Place Historic District |
| East Third Street Historic District |
| East Toledo Historic District |
| East Toledo Main Street Historic District |
| East Walnut Hills Firehouse |
| Eastwood Historic District |
| Eaton High School |
| Eckenrode And Breisach Houses |
| Eckert Building |
| Eckis, Nicholas, House |
| Edgecliff Area Historic Group |
| Edgeton |
| Edgington Mound |
| Edna, The |
| Edwards Gymnasium/Pfieffer Natatorium |
| Edwards, John, House |
| Edwards, John Stark, House |
| Edwards, William, Farmhouse |
| Edward Wren Company Building |
| E.F. Hauserman Co. Administration, Engineering & Research Building |
| Ehresman, Christian, Farm |
| Eiden Prehistoric District |
| Elden House |
| Eldridge-Higgins Building |
| Eleanor B. Rainey Memorial Institute |
| Elizabeth Township Rural Historic District |
| Elk Lick Road Mound |
| Elks Club |
| Elks Lodge |
| Elliot House |
| Elliott House |
| Ellis Mounds |
| Elmdale Grange Hall 2162 and Watson One-Room School |
| Elmwood Place |
| Elson-Magnolia Flour Mill |
| Ely Block |
| Elyria Downtown-West Avenue Historic District |
| Elyria Elks Club |
| Elyria High School - Washington Building |
| Emanuel Lutheran Church of Montra |
| Emery Hall |
| Emmanuel Church |
| Emmanuel's Evangelical Lutheran Church |
| Empire House |
| Empire Junior High School |
| Engels And Krudwig Wine Company Buildings |
| Engels, Herman, House |
| Engineers Club of Dayton |
| Engine House No. 1 |
| Engine House No. 16 |
Data from United States Park Service and Wikidata
